The Centers for Disease Control and Prevention definition of mucosal barrier injury-associated bloodstream infection improves accurate detection of preventable bacteremia rates at a pediatric cancer center in a low- to middle-income country

American Journal of Infection Control
Dara TorresMiguela A Caniza

Abstract

The US National Healthcare Safety Network has provided a definition of mucosal barrier injury-associated, laboratory-confirmed bloodstream infection (MBI-LCBI) to improve infection surveillance. To date there is little information about its influence in pediatric oncology centers in low- to middle-income countries. To determine the influence of the definition on the rate of central line-associated bloodstream infection (CLABSI) and compare the clinical characteristics of MBI versus non-MBI LCBI cases. We retrospectively applied the National Healthcare Safety Network definition to all CLABSIs recorded at a pediatric oncology center in Tijuana, Mexico, from January 2011 through December 2014. CLABSI events were reclassified according to the MBI-LCBI definition. Clinical characteristics and outcomes of MBI and non-MBI CLABSIs were compared. Of 55 CLABSI events, 44% (24 out of 55) qualified as MBI-LCBIs; all were MBI-LCBI subcategory 1 (intestinal flora pathogens). After the number of MBI-LCBI cases was removed from the numerator, the CLABSI rate during the study period decreased from 5.72-3.22 infections per 1,000 central line days. Patients with MBI-LCBI were significantly younger than non-MBI-LCBI patients (P = .029) and had a s...Continue Reading

References

Nov 13, 2007·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·Miguela A CanizaElaine I Tuomanen
Oct 29, 2010·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·Daniel J SextonDeverick J Anderson
Jun 2, 2011·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Thomas G Fraser, Steven M Gordon
Sep 13, 2011·American Journal of Infection Control·Victor D RosenthalUNKNOWN INICC members
Feb 8, 2013·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·Aditya H GaurUNKNOWN Children's Hospital Association Hematology-Oncology Quality Transformation Collaborative Project
Mar 30, 2013·American Journal of Infection Control·Margaret A DudeckJonathan R Edwards
Jun 7, 2013·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·Aditya H GaurW Charles Huskins
Jul 11, 2013·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·Isaac SeeNicola D Thompson
Jul 11, 2013·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·James P Steinberg, Susan E Coffin
Nov 28, 2013·American Journal of Infection Control·Margaret A DudeckJonathan R Edwards
Jan 13, 2015·American Journal of Infection Control·Margaret A DudeckDawn M Sievert
Jan 31, 2015·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·Kristen E MetzgerMaureen K Bolon

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Citations

Mar 22, 2018·Journal of Pediatric Oncology Nursing : Official Journal of the Association of Pediatric Oncology Nurses·Chelsea BalianJessica Ward
Nov 18, 2018·Critical Care Medicine·Naomi P O'Grady, Sameer S Kadri
May 10, 2020·Pediatric Blood & Cancer·Hana HakimUNKNOWN Children's Hospital Association Childhood Cancer and Blood Disorders Network
Jul 23, 2019·Expert Review of Pharmacoeconomics & Outcomes Research·Paula Rojas García, Fernando Antoñanzas Villar

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