Abstract
The US National Healthcare Safety Network has provided a definition of mucosal barrier injury-associated, laboratory-confirmed bloodstream infection (MBI-LCBI) to improve infection surveillance. To date there is little information about its influence in pediatric oncology centers in low- to middle-income countries. To determine the influence of the definition on the rate of central line-associated bloodstream infection (CLABSI) and compare the clinical characteristics of MBI versus non-MBI LCBI cases. We retrospectively applied the National Healthcare Safety Network definition to all CLABSIs recorded at a pediatric oncology center in Tijuana, Mexico, from January 2011 through December 2014. CLABSI events were reclassified according to the MBI-LCBI definition. Clinical characteristics and outcomes of MBI and non-MBI CLABSIs were compared. Of 55 CLABSI events, 44% (24 out of 55) qualified as MBI-LCBIs; all were MBI-LCBI subcategory 1 (intestinal flora pathogens). After the number of MBI-LCBI cases was removed from the numerator, the CLABSI rate during the study period decreased from 5.72-3.22 infections per 1,000 central line days. Patients with MBI-LCBI were significantly younger than non-MBI-LCBI patients (P = .029) and had a s...Continue Reading
References
Nov 13, 2007·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·Miguela A CanizaElaine I Tuomanen
May 27, 2008·BMC Infectious Diseases·Arne SimonMichael H Kramer
Jun 10, 2008·American Journal of Infection Control·Teresa C HoranMargaret A Dudeck
Oct 29, 2010·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·Daniel J SextonDeverick J Anderson
Dec 29, 2010·PloS One·Walter J F M van der VeldenNicole M A Blijlevens
Jun 2, 2011·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·Thomas G Fraser, Steven M Gordon
Sep 13, 2011·American Journal of Infection Control·Victor D RosenthalUNKNOWN INICC members
Feb 8, 2013·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·Aditya H GaurUNKNOWN Children's Hospital Association Hematology-Oncology Quality Transformation Collaborative Project
Mar 30, 2013·American Journal of Infection Control·Margaret A DudeckJonathan R Edwards
Jun 7, 2013·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·Aditya H GaurW Charles Huskins
Jul 11, 2013·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·Isaac SeeNicola D Thompson
Jul 11, 2013·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·James P Steinberg, Susan E Coffin
Nov 28, 2013·American Journal of Infection Control·Margaret A DudeckJonathan R Edwards
Jan 4, 2015·American Journal of Infection Control·Peggy Ann HazamyEmily Lutterloh
Jan 13, 2015·American Journal of Infection Control·Margaret A DudeckDawn M Sievert
Jan 31, 2015·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·Kristen E MetzgerMaureen K Bolon
Citations
Dec 22, 2016·Pediatric Blood & Cancer·Paula AristizabalWilliam Roberts
Mar 28, 2017·Bone Marrow Transplantation·C E DandoyJ J Auletta
Mar 22, 2018·Journal of Pediatric Oncology Nursing : Official Journal of the Association of Pediatric Oncology Nurses·Chelsea BalianJessica Ward
Nov 18, 2018·Critical Care Medicine·Naomi P O'Grady, Sameer S Kadri
Aug 8, 2019·Leukemia & Lymphoma·Nicholas ScrivensSheryl McDiarmid
Dec 7, 2018·Blood Advances·Mario Ornelas-SánchezPaula Aristizabal
May 10, 2020·Pediatric Blood & Cancer·Hana HakimUNKNOWN Children's Hospital Association Childhood Cancer and Blood Disorders Network
Jul 23, 2019·Expert Review of Pharmacoeconomics & Outcomes Research·Paula Rojas García, Fernando Antoñanzas Villar
Nov 9, 2019·Epidemiology and Infection·M M GarridoI S Martins
Feb 13, 2020·JCO Oncology Practice·Daniel ReedMichael Keng
Mar 7, 2021·Pediatric Radiology·Kevin S H KooDanielle M Zerr
May 12, 2021·JCO Global Oncology·Miriam L GonzalezMiguela A Caniza