The Centre for Trophoblast Research: improving health through placental research

Reproductive Biomedicine Online
Graham J Burton

Abstract

The placenta is an essential but widely neglected organ. As the interface between the mother and her fetus, the placenta represents the platform for a healthy life. The majority of the major complications of pregnancy, including miscarriage, pre-eclampsia, intrauterine growth restriction and stillbirth, have their pathophysiological roots in poor placentation. In addition, there is now irrefutable evidence that low birthweight predisposes to a higher risk of cardiovascular and other disorders in later life. The Centre for Trophoblast Research was established in the University of Cambridge with the aim of generating new impetus and a fresh approach to address these problems. Placentation involves many different cell biological processes, some of which are unique to the trophoblast, as well as complex interactions with the maternal immune system. The Centre brings together academic clinicians and basic scientists working in diverse disciplines and provides a rich intellectual environment that facilitates novel collaborative links. The Centre also encourages new investigators into the field and fosters their careers through a number of initiatives, including support for studentships and fellowships, developing research resources, ...Continue Reading

References

Jun 7, 2002·The Journal of Clinical Endocrinology and Metabolism·Graham J BurtonEric Jauniaux
Sep 8, 2004·Journal of the Society for Gynecologic Investigation·Graham J Burton, Eric Jauniaux
Oct 7, 2008·Nature Cell Biology·Ray Kit NgMyriam Hemberger
Nov 21, 2008·BMC Pregnancy and Childbirth·Dharmintra PasupathyGordon C S Smith
Oct 26, 2010·The Journal of Clinical Investigation·Susan E HibyAshley Moffett

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Citations

May 15, 2012·Reproductive Biomedicine Online·Rosalind John, Myriam Hemberger

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