The cerebral arterio-venous oxygen content differences (AVDO2) during halothane and neurolept anaesthesia in patients subjected to craniotomy

Acta Anaesthesiologica Scandinavica
M EngbergG E Cold

Abstract

In 20 patients subjected to craniotomy for supratentorial cerebral tumours, the haemodynamic changes during halothane and neurolept anaesthesia were evaluated by measuring mean arterial blood pressure (MABP) and cerebral arterio-venous oxygen content differences (AVDO2) repeatedly during the operation. Ten patients were given 0.5% halothane anaesthesia and ten patients neurolept anaesthesia. MABP, AVDO2 and PaCO2 were measured after induction of anaesthesia, before and after incision, after opening and closure of the dura, at the time of extubation and 1 h later. Concerning MABP and PaCO2, no significant difference between the two groups was found. In both groups an increase in MABP was observed after incision (P less than 0.01 in the neurolept group and P less than 0.05 in the halothane group) and in the neurolept group after extubation (P less than 0.01). In both groups a decrease in AVDO2 was observed after incision (P less than 0.01) and after extubation (P less than 0.01 in the neurolept group and P less than 0.05 in the halothane group). During the operation AVDO2 values were significantly higher in the neurolept group (P less than 0.05). The results indicate that even a moderate increase in MABP after incision during neu...Continue Reading

References

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Citations

Mar 17, 2016·Surgical Neurology International·George FotakopoulosKostas N Fountas
Feb 22, 2008·Best Practice & Research. Clinical Anaesthesiology·Armin Schubert
Feb 28, 2002·Anesthesia and Analgesia·Nicolas BruderFrançois Gouin
Jun 1, 1992·Perceptual and Motor Skills·D Koulack, M Nesca
Jun 3, 2008·Neurologic Clinics·Leonardo Rangel-CastillaClaudia S Robertson

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