Dec 31, 2002

The cerebral circulation during sleep: regulation mechanisms and functional implications

Sleep Medicine Reviews
G ZoccoliC Franzini

Abstract

Cerebral blood flow measurements during sleep are reviewed and discussed in relation to the different techniques utilized (Positron Emission Tomography, functional Magnetic Resonance Imaging, Flowmeters, Radioactive MicroIspheres, Brain Temperature Recordings, Spectrophotometry) since these methodological approaches aim at diverse features of circulation changes in the spatial or temporal domain. The regulation of cerebral circulation during sleep reveals no specific state-dependent features, flow-activity coupling being the prevailing mechanism, with O(2) as the primary candidate for the metabolic side of the link. On a general level, the latest data on brain circulation are compatible with the classical hypothesis of a "restorative" function of sleep processes.

Mentioned in this Paper

Metabolic Process, Cellular
Cerebral Blood Flow Imaging
Positron-Emission Tomography
Brain
Tomography, Emission-Computed
Sleep Stages
Spectrophotometry, Analyte Not Elsewhere Specified in CPT
FMRI
Cerebrovascular Circulation
Spectrophotometry

About this Paper

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