The challenge of developing evidence-based genetics health care in practice

Familial Cancer
Brenda J Wilson

Abstract

Evidence-based genetics health care is the conscientious use of current best evidence in decision-making at the clinical, administrative and policy-making levels. As knowledge generated from genomics research is integrated into medical care, the needs for appropriate evidence become more complex. The challenges to evidence-based care include: a lack of policy-relevant evidence in the domains of basic, clinical and health services research (including ethical, legal and social issues); difficulties in translating knowledge into appropriate decisions and actions, particularly in relation to the capacity of audiences to interpret evidence; and competing perspectives on the nature of evidence in genetics and genomics. In meeting these challenges, lessons will be learnt which are likely to be relevant to emerging biotechnologies and health care development more generally.

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Citations

Apr 5, 2014·American Journal of Medical Genetics. Part a·Ghayda M MirzaaAlex R Paciorkowski
Apr 7, 2010·Journal of Evaluation in Clinical Practice·Abeer S H AhmadLukman Thalib
Aug 19, 2014·Journal of Evaluation in Clinical Practice·Homayoun Sadeghi-BazarganiSaber Azami-Aghdash
May 17, 2012·Journal of Evaluation in Clinical Practice·Maritta Kinnunen-Amoroso
Nov 12, 2010·Genetics in Medicine : Official Journal of the American College of Medical Genetics·Yulong GuKaren Jean Day

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