Abstract
Evidence-based genetics health care is the conscientious use of current best evidence in decision-making at the clinical, administrative and policy-making levels. As knowledge generated from genomics research is integrated into medical care, the needs for appropriate evidence become more complex. The challenges to evidence-based care include: a lack of policy-relevant evidence in the domains of basic, clinical and health services research (including ethical, legal and social issues); difficulties in translating knowledge into appropriate decisions and actions, particularly in relation to the capacity of audiences to interpret evidence; and competing perspectives on the nature of evidence in genetics and genomics. In meeting these challenges, lessons will be learnt which are likely to be relevant to emerging biotechnologies and health care development more generally.
References
Sep 1, 1989·Theoretical Medicine·G Mooney
Aug 1, 1967·Journal of Chronic Diseases·D Schwartz, J Lellouch
Jan 13, 1996·BMJ : British Medical Journal·D L SackettW S Richardson
Sep 29, 1999·Social Science & Medicine·P A Coventry, J V Pickstone
Jan 6, 2001·Journal of Health Politics, Policy and Law·P Lehoux, S Blume
Jul 20, 2001·British Journal of Cancer·D WonderlingK McPherson
May 3, 2003·Trends in Molecular Medicine·John P A Ioannidis
Jul 17, 2003·International Journal of Technology Assessment in Health Care·Mita GiacominiGeorge Browman
Jul 17, 2003·Genetics in Medicine : Official Journal of the American College of Medical Genetics·Muin J Khoury
Sep 25, 2003·JAMA : the Journal of the American Medical Association·Sean R TunisCarolyn M Clancy
Dec 5, 2003·The Journal of Hospital Infection·C M PelloweUNKNOWN Guideline Development Group
Jan 22, 2004·Journal of the National Cancer Institute·Dejana BraithwaiteStephen Sutton
May 25, 2004·BMJ : British Medical Journal·Martin Grann, Seena Fazel
Jun 24, 2004·British Journal of Cancer·U HerrlingerM Weller
Aug 21, 2004·International Journal of Epidemiology·Muin J KhouryMarta Gwinn
Nov 20, 2004·BMJ : British Medical Journal·Joanna Coast
Jan 18, 2005·Genetics in Medicine : Official Journal of the American College of Medical Genetics·Monica R McClainJames E Haddow
Jun 7, 2005·Genetics·Hiroji ChibanaYuzuru Mikami
Feb 18, 2006·Journal of Health Politics, Policy and Law·Patricia M Pittman
Citations
Jun 23, 2009·BMC Medical Ethics·Alethea AdairTimothy Caulfield
Apr 5, 2014·American Journal of Medical Genetics. Part a·Ghayda M MirzaaAlex R Paciorkowski
May 24, 2011·Chronic Illness·Holly Etchegary
Jun 7, 2006·Leukemia & Lymphoma·R M SwinneyG E Tomlinson
Apr 7, 2010·Journal of Evaluation in Clinical Practice·Abeer S H AhmadLukman Thalib
Mar 20, 2012·PloS One·Vivian WelchPeter Tugwell
Aug 19, 2014·Journal of Evaluation in Clinical Practice·Homayoun Sadeghi-BazarganiSaber Azami-Aghdash
May 17, 2012·Journal of Evaluation in Clinical Practice·Maritta Kinnunen-Amoroso
Nov 12, 2010·Genetics in Medicine : Official Journal of the American College of Medical Genetics·Yulong GuKaren Jean Day