The challenge of forgetting: Neurobiological mechanisms of auditory directed forgetting

Human Brain Mapping
Olga L GamboaHelmuth Steinmetz

Abstract

Directed forgetting (DF) is considered an adaptive mechanism to cope with unwanted memories. Understanding it is crucial to develop treatments for disorders in which thought control is an issue. With an item-method DF paradigm in an auditory form, the underlying neurocognitive processes that support auditory DF were investigated. Subjects were asked to perform multi-modal encoding of word-stimuli before knowing whether to remember or forget each word. Using functional magnetic resonance imaging, we found that DF is subserved by a right frontal-parietal-cingulate network. Both qualitative and quantitative analyses of the activation of this network show converging evidence suggesting that DF is a complex process in which active inhibition, attentional switching, and working memory are needed to manipulate both unwanted and preferred items. These results indicate that DF is a complex inhibitory mechanism which requires the crucial involvement of brain areas outside prefrontal regions to operate over attentional and working memory processes. Hum Brain Mapp 39:249-263, 2018. © 2017 Wiley Periodicals, Inc.

References

Sep 1, 1992·Cortex; a Journal Devoted to the Study of the Nervous System and Behavior·E CapitaniH Spinnler
Nov 5, 1997·NeuroImage·K J FristonR J Dolan
Apr 16, 1999·Nature Neuroscience·R L BucknerS E Petersen
Jul 8, 1999·Proceedings of the National Academy of Sciences of the United States of America·H GaravanE A Stein
Apr 19, 2000·Journal of Cognitive Neuroscience·R Cabeza, L Nyberg
Jul 27, 2000·Human Brain Mapping·J L LancasterP T Fox
Mar 27, 2001·Nature·M C Anderson, C Green
Feb 22, 2003·NeuroImage·Susanne ErkHenrik Walter
Oct 31, 2003·Cortex; a Journal Devoted to the Study of the Nervous System and Behavior·Martin A Conway, Aikaterina Fthenaki
Jan 20, 2007·Science·Malia F MasonC Neil Macrae
Jun 17, 2008·Nature Neuroscience·Dimitris TsivilisJohn P Aggleton
Oct 18, 2008·Memory & Cognition·Jonathan M Fawcett, Tracy L Taylor
Nov 26, 2008·Neurobiology of Learning and Memory·Melina R Uncapher, Anthony D Wagner
Dec 17, 2008·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Maria WimberAlan Richardson-Klavehn
Apr 14, 2009·Behavior Research Methods·Melissa L-H VõArthur M Jacobs
Jun 30, 2010·Cerebral Cortex·Anna NowickaAndré Brechmann
Mar 4, 2011·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Robert LeechDavid J Sharp
Mar 23, 2011·Trends in Cognitive Sciences·John M PearsonMichael L Platt
Jun 28, 2011·Nature Methods·Tal YarkoniTor D Wager
Sep 24, 2011·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Valerie BonnelleDavid J Sharp
Mar 1, 2012·The Quarterly Journal of Experimental Psychology : QJEP·Yuh-Shiow Lee
Mar 1, 2012·Neuroscience and Biobehavioral Reviews·Brendan E Depue
Mar 7, 2012·Proceedings of the National Academy of Sciences of the United States of America·Valerie BonnelleDavid J Sharp
Oct 23, 2012·Neuron·Roland G Benoit, Michael C Anderson
Feb 2, 2013·Trends in Cognitive Sciences·Oliver HardtLynn Nadel
Jul 23, 2013·Brain : a Journal of Neurology·Robert Leech, David J Sharp
Apr 22, 2014·Trends in Cognitive Sciences·Michael C Anderson, Simon Hanslmayr
Mar 19, 2015·Frontiers in Systems Neuroscience·Shruti JapeeLeslie G Ungerleider

❮ Previous
Next ❯

Related Concepts

Related Feeds

Auditory Perception

Auditory perception is the ability to receive and interpret information attained by the ears. Here is the latest research on factors and underlying mechanisms that influence auditory perception.