The change in management of bronchiolitis in the intensive care unit between 2000 and 2015

European Journal of Pediatrics
Minna MecklinMatti Korppi

Abstract

This case-control study evaluated interventions for bronchiolitis in relation to time in the pediatric intensive care unit (PICU) during a 16-year surveillance period. Together, 105 infants aged < 12 months were treated for bronchiolitis in the PICU, and for them, we selected 210 controls admitted for bronchiolitis closest to cases. We collected data on treatments in the PICU, at the ward and in the emergency department for three periods: years 2000-2005, 2006-2010, and 2011-2015. Median hospital length of stay for PICU patients were 7 days (interquartile range 5-12), 5 days (4-8) and 8 days (4-12.5, p = 0.127), respectively. By time, the use of inhaled beta-agonist (68 vs. 44 vs. 38%, p = 0.019) and systemic corticosteroids (29 vs. 15 vs. 5%, p = 0.019) decreased, but that of racemic adrenaline (59 vs. 78 vs. 84%, p = 0.035) and hypertonic saline (0 vs. 0 vs. 54%, p < 0.001) inhalations increased in the PICU. Similar changes were seen at the ward. In the PICU, non-invasive ventilation therapies increased significantly, but intubation rates did not decline.Conclusion: Beta-agonists and systemic corticosteroids were used less by time in intensive care for infant bronchiolitis, but the use of hypertonic saline and racemic adrenal...Continue Reading

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Citations

Nov 30, 2018·Expert Review of Respiratory Medicine·Matti Korppi
Feb 13, 2019·European Journal of Pediatrics·Maria Chiara SupinoAnna Maria Musolino
Jan 30, 2020·Acta Paediatrica·Matti Korppi
Sep 9, 2020·American Journal of Perinatology·Steve Cunningham
Dec 20, 2020·Archives de pédiatrie : organe officiel de la Sociéte française de pédiatrie·A Marcos-MoralesJ Casado-Flores
Oct 31, 2020·Pharmacology & Therapeutics·Farah ElawarDavid J Marchant
Mar 13, 2021·JMIR Medical Informatics·Alicia Martinez-GarciaCarlos Luis Parra Calderón

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