The changes in brain surface, intracerebral tissue, and transconjunctival oxygen tension during hypo- and hyperventilation

Journal of Anesthesia
T AraiD E Lees

Abstract

To evaluate the validity of organ surface oxygen tension monitoring for assessment of cerebral perfusion, the oxygen tension in brain surface (Pbs(O)(2)), intracerebral tissue (Pic(O)(2)), and conjunctiva (Pcj(O)(2)) were measured simultaneously during hypo- and hyperventilation in dogs, and the comparative study was done. Pbs(O)(2) and Pic(O)(2) significantly increased during hypoventilation and decreased during hyperventilation. And the values of Pbs(O)(2) and Pic(O)(2) were correlated to the corresponding Pa(CO)(2) values significantly ( P < 0.001 in each case). On the contrary, Pcj(O)(2) did not change significantly during hypo- and hyperventilation. These findings indicate that Pbs(O)(2) as well as Pic(O)(2) could reflect the changes in cerebral perfusion caused by induced hyper- and hypocapnia but that Pcj(O)(2) could not.

References

Sep 1, 1987·Critical Care Medicine·T AraiK Mori
Aug 1, 1986·Critical Care Medicine·H B KramW C Shoemaker
Jan 1, 1985·Advances in Experimental Medicine and Biology·N Lund
Jan 1, 1986·Critical Care Medicine·M NisamC J Fisher
Jan 1, 1985·Anesthesia and Analgesia·H T van der ZeeW Erdmann
Oct 1, 1985·Critical Care Medicine·N BratanowW C Shoemaker
Oct 1, 1974·Anesthesiology·D J Cullen, E I Eger
Jun 1, 1974·Circulation Research·N A Lassen
Nov 1, 1971·Journal of Applied Physiology·H MetzgerG Thews
Jan 1, 1964·The American Journal of Physiology·M REIVICH

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