The changing face of the cost-utility literature, 1990-2012

Value in Health : the Journal of the International Society for Pharmacoeconomics and Outcomes Research
Peter J NeumannJoshua T Cohen

Abstract

Cost-utility analyses (CUAs) have been published widely over the years to measure the value of health care interventions. We investigated the growth and characteristics of CUAs in the peer-reviewed English-language literature through 2012. We analyzed data from the Tufts Medical Center Cost-Effectiveness Analysis (CEA) Registry, a database containing more than 3700 English-language CUAs published through 2012. We summarized various study characteristics (e.g., intervention type, funding source, and journal of publication) and methodological practices (e.g., use of probabilistic sensitivity analysis) over three time periods: 1990 to 1999, 2000 to 2009, and 2010 to 2012. We also examined CUAs by country, region, and the degree to which diseases studied correlate with disease burden. The number of published CUAs rose from 34 per year from 1990 to 1999 to 431 per year from 2010 to 2012. The proportion of studies focused on the United States declined from 61% during 1990 to 1999 to 35% during 2010 to 2012 (P < 0.0001). Although still small compared with CUAs in higher income countries, the number of CUAs focused on lower and middle-income countries has risen sharply. A large fraction of studies pertain to pharmaceuticals (46% during...Continue Reading

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Citations

Jan 7, 2016·Expert Review of Pharmacoeconomics & Outcomes Research·Tzahit Simon-TuvalDan Greenberg
Oct 20, 2015·Expert Review of Pharmacoeconomics & Outcomes Research·Natalia OlchanskiPeter J Neumann
Oct 17, 2015·American Journal of Preventive Medicine·Aaron N WinnPeter J Neumann
Aug 28, 2016·Value in Health : the Journal of the International Society for Pharmacoeconomics and Outcomes Research·Louis P Garrison
Sep 16, 2016·American Journal of Public Health·Peter J NeumannMarthe Gold
Nov 1, 2016·Applied Health Economics and Health Policy·Alessandro G CampolinaPatrícia Coelho De Soárez
May 12, 2017·Medical Decision Making : an International Journal of the Society for Medical Decision Making·Ankur PandyaThomas A Gaziano
May 16, 2017·Expert Review of Pharmacoeconomics & Outcomes Research·David D KimPeter J Neumann
Nov 20, 2015·Medical Decision Making : an International Journal of the Society for Medical Decision Making·Jeff RichardsonAimee Maxwell
Nov 5, 2016·The Annals of Pharmacotherapy·Alex L WoerschingDennis W Raisch
Oct 3, 2018·Clinical Otolaryngology : Official Journal of ENT-UK ; Official Journal of Netherlands Society for Oto-Rhino-Laryngology & Cervico-Facial Surgery·Machteld M H T van EgmondMaroeska M Rovers
Jan 21, 2020·Annals of Internal Medicine·Ryan CrowleyUNKNOWN Health and Public Policy Committee of the American College of Physicians
Apr 29, 2020·International Journal of Technology Assessment in Health Care·Xue FengDaniel A Ollendorf
Jun 5, 2020·Obesity Reviews : an Official Journal of the International Association for the Study of Obesity·Qing XiaAndrew J Palmer
Aug 1, 2016·Applied Health Economics and Health Policy·Kittiphong ThiboonboonYot Teerawattananon
Jan 20, 2018·Medical Decision Making : an International Journal of the Society for Medical Decision Making·Tara A LavellePeter J Neumann
Oct 24, 2018·Applied Health Economics and Health Policy·Tara A LavellePei-Jung Lin
May 9, 2019·PharmacoEconomics·Joanna EmersonJoshua T Cohen
Apr 29, 2020·PharmacoEconomics·Michelle Q T KwokJames F O'Mahony
Jul 12, 2017·Health Economics·Julia F SlejkoSean D Sullivan
Jun 15, 2019·Orphanet Journal of Rare Diseases·Panayiotis KouisPanayiotis K Yiallouros
Feb 13, 2018·Gates Open Research·Peter J NeumannJoshua T Cohen
Mar 25, 2019·Medical Decision Making : an International Journal of the Society for Medical Decision Making·Feng XieGordon Guyatt
Jul 23, 2020·PharmacoEconomics·David D KimPeter J Neumann
Mar 16, 2018·Frontiers in Public Health·Tassia Cristina DecimoniPatrícia Coelho de Soárez
Jan 16, 2019·JAMA Network Open·Peter W Groeneveld
Feb 15, 2018·PharmacoEconomics Open·Kavisha JayasundaraPaul Grootendorst
Mar 2, 2021·Value in Health : the Journal of the International Society for Pharmacoeconomics and Outcomes Research·Isaac Aranda-ReneoJulio López-Bastida
Feb 6, 2021·Journal of Medical Economics·Panagiotis Petrou
May 7, 2021·ClinicoEconomics and Outcomes Research : CEOR·Beatriz Rodriguez-SanchezJulio Lopez-Bastida
May 21, 2019·Value in Health : the Journal of the International Society for Pharmacoeconomics and Outcomes Research·Julia F SlejkoSusan dosReis

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