The changing scenario in laboratory medicine and the role of laboratory professionals in translational medicine

Clinica Chimica Acta; International Journal of Clinical Chemistry
Mario Plebani

Abstract

A revolution is now expected to occur in the ever-changing scenario of laboratory medicine thanks to the introduction of "omics" into clinical practice. However, our awareness of the divide between knowledge and practice, and the understandable assumption that omics research will be riddled with difficulties, has led to the concepts of knowledge translation, translational research and translational medicine. The interchangeable terms, translational research or translational medicine (hereafter referred to as translational research), currently underline the pressing need to gain practical benefit from the enormous investments made in biomedical research by the private and public sector. From the viewpoint of physicians, clinical laboratory professionals and patients, who are more directly involved in clinical practice, translational research responds to the need to obtain benefit from research, thus closing the gap between what we know and what we practice. This means transferring diagnostic and therapeutic advances that have proven effective in large well-conducted trials (and are therefore evidenced-based,) to daily medical practice. Translational research should be regarded as a two-way road: bench to bedside, and bedside to ...Continue Reading

References

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Jul 6, 2004·Clinica Chimica Acta; International Journal of Clinical Chemistry·Mario Plebani
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Citations

May 17, 2011·Source Code for Biology and Medicine·Timothy G BathDaniel Crowther
Apr 29, 2009·Clinical Chemistry and Laboratory Medicine : CCLM·Giuseppe LippiEmmanuel J Favaloro
Aug 1, 2009·Clinical Chemistry and Laboratory Medicine : CCLM·Mario Plebani, Giuseppe Lippi
Oct 30, 2009·Clinical Chemistry and Laboratory Medicine : CCLM·María Concepción Alonso-CerezoVerónica Marcos de la Iglesia
Dec 6, 2011·Biotechnology Advances·Fa-Ming ChenSongtao Shi
Nov 19, 2014·Clinical Chemistry and Laboratory Medicine : CCLM·Mario Plebani
Jun 25, 2016·Clinical Chemistry and Laboratory Medicine : CCLM·Giorgio LiguoriMario Plebani

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