The changing susceptibilities of methicillin-resistant Staphylococcus aureus at a midwestern hospital: the emergence of "community-associated" MRSA

American Journal of Infection Control
Kathleen M McMullenKeith F Woeltje

Abstract

The emergence of community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) has been well described; however, few studies have reviewed long-term hospital-wide data. This retrospective study of adult patients used the first culture per patient per visit positive for MRSA for 1996 to 2005. Isolates were categorized as community-associated or health care-associated phenotype based on antibiotic susceptibilities. chi(2) tests for trend and linear regression analyses were performed. The annual prevalence of CA-MRSA increased significantly over the 10-year study period (from 43 of 507 [8.9%] MRSA cultures in 1996 to 672 of 1697 [39.6%] MRSA cultures in 2005; P < .01). The proportion of MRSA cultures obtained within 48 hours of hospital admission increased from 50.5% to 79.5% (P < .01). The median age of patients with MRSA decreased, from 60 to 49 years (P < .01). Among the CA-MRSA cases, the proportion of non-Caucasian patients increased from 30.2% to 60.4% (P < .01) and the proportion of patients categorized as low socioeconomic status increased from 25.6% to 35.6% (P < .01). Significant consistent trends were not observed for patient sex or body sites of the cultures. An increasing number of MRSA with a community-a...Continue Reading

References

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Citations

Jul 27, 2011·Current Infectious Disease Reports·Isaac Thomsen, C Buddy Creech
Mar 30, 2011·Antimicrobial Agents and Chemotherapy·Megan H NguyenLoren G Miller
Mar 24, 2012·American Journal of Infection Control·William R JarvisRaymond Y Chinn
Feb 14, 2013·International Forum of Allergy & Rhinology·Andrea S WangAaron N Pearlman
May 9, 2013·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·Courtney R MurphySusan S Huang
Sep 15, 2017·Infection Control and Hospital Epidemiology : the Official Journal of the Society of Hospital Epidemiologists of America·M Ellen AcreeMichael Z David
Aug 18, 2018·Infectious Diseases of Poverty·Vivian AlividzaEnrique Castro-Sánchez

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