The changing treatment landscape in idiopathic pulmonary fibrosis

European Respiratory Review : an Official Journal of the European Respiratory Society
U Costabel

Abstract

Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive and irreversible fibrotic disease of the lung that has greatly frustrated clinicians for a long time. The prognosis of IPF (median survival 2-5 years following diagnosis) is poorer than that of some cancers and for many years no significant advances were made in its management. However, between 2011 and 2014 a number of pivotal developments were made that have improved the outlook for patients with IPF. Herein, we review this rapidly changing landscape, discussing key events whilst still acknowledging that IPF remains a challenging disease to diagnose and manage.

References

Apr 16, 2003·Respiratory Medicine·C von PlessenA Gulsvik
Jun 2, 2006·Proceedings of the American Thoracic Society·Dong Soon KimTalmadge E King
Jun 23, 2007·American Journal of Respiratory and Critical Care Medicine·Harold R CollardUNKNOWN Idiopathic Pulmonary Fibrosis Clinical Research Network Investigators
Mar 28, 2008·Orphanet Journal of Rare Diseases·Eric B Meltzer, Paul W Noble
Apr 7, 2009·Respiratory Medicine·A KarakatsaniUNKNOWN Hellenic Interstitial Lung Diseases Group
Oct 12, 2010·American Journal of Respiratory and Critical Care Medicine·Brett LeyTalmadge E King
Mar 1, 2011·Women's Health Issues : Official Publication of the Jacobs Institute of Women's Health·Susan F WoodD Richard Mauery
Apr 8, 2011·American Journal of Respiratory and Critical Care Medicine·Ganesh RaghuUNKNOWN ATS/ERS/JRS/ALAT Committee on Idiopathic Pulmonary Fibrosis
Apr 29, 2011·Thorax·V NavaratnamR B Hubbard
May 17, 2011·Lancet·Paul W NobleUNKNOWN CAPACITY Study Group
May 9, 2012·American Journal of Respiratory and Critical Care Medicine·Imre NothUNKNOWN Idiopathic Pulmonary Fibrosis Clinical Research Network (IPFnet)
Oct 30, 2012·Immunology and Allergy Clinics of North America·Toby M Maher
Feb 21, 2013·Deutsche medizinische Wochenschrift·F BonellaU Costabel
Apr 20, 2013·The European Respiratory Journal·Jean-François Cordier, Vincent Cottin
Feb 20, 2014·American Journal of Respiratory and Critical Care Medicine·Rachel K PutmanGary M Hunninghake
Mar 19, 2014·Respiratory Investigation·Toru AraiSeiji Hayashi
May 20, 2014·The New England Journal of Medicine·Fernando J MartinezGanesh Raghu
May 20, 2014·The New England Journal of Medicine·Luca RicheldiUNKNOWN INPULSIS Trial Investigators
May 20, 2014·The New England Journal of Medicine·Talmadge E KingUNKNOWN ASCEND Study Group
May 20, 2014·Respirology : Official Journal of the Asian Pacific Society of Respirology·Dominique ValeyreRoland M du Bois
Dec 3, 2014·The Lancet. Respiratory Medicine·Wim A WuytsAthol U Wells

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Citations

Apr 16, 2016·BMC Pulmonary Medicine·Domokos BartisDavid R Thickett
Mar 16, 2017·Archivos de bronconeumología·Antoni XaubetJulio Ancochea
Sep 28, 2018·Experimental Physiology·Lauren HeadleyHarry Karmouty-Quintana
Sep 2, 2015·European Respiratory Review : an Official Journal of the European Respiratory Society·Sergio Harari, Antonella Caminati
Nov 30, 2018·Cadernos de saúde pública·Neuciani Ferreira da Silva SousaMarilisa Berti de Azevedo Barros
Nov 7, 2019·Journal of Cellular and Molecular Medicine·Mi-Hyoung KimJie-Young Song
Apr 6, 2021·Journal of Pharmacological and Toxicological Methods·R CarringtonC P Page
Jul 4, 2021·Bioorganic & Medicinal Chemistry Letters·Yue BaiXiaodong Ma

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