The chemistry of lysozyme and its use as a food preservative and a pharmaceutical

Critical Reviews in Food Science and Nutrition
V A Proctor, F E Cunningham


The chemistry and use of lysozyme as a food preservative and a pharmaceutical are reviewed. Lysozyme inhibits the growth of deleterious organisms, thus prolonging shelf life. Chemicals used to improve the preservative effect of lysozyme and those that inhibit the enzyme are discussed, along with the stability of lysozyme in various chemical environments. Lysozyme has been used to preserve fresh fruits and vegetables, tofu bean curd, seafoods, meats and sausages, potato salad, cooked burdock with soy sauce, and varieties of semihard cheeses such as Edam, Gouda, and some Italian cheeses. Lysozyme added to infant-feeding formulas makes them more closely resemble human milk. Lysozyme has been used clinically in the treatment of periodontitis, administered in chewing gum, and implemented to prevent tooth decay. It has also been administered to patients suffering from cancer for its analgesic effect and has been used as a potentiating agent in antibiotic therapy.


Sep 9, 1975·Biochimica Et Biophysica Acta·M Tribout, J Léonis
May 1, 1977·American Journal of Clinical Pathology·T KageokaS Miwa
Jan 1, 1979·Proceedings of the National Academy of Sciences of the United States of America·M C Nguyen-HuuG Schütz
Sep 1, 1978·Analytical Chemistry·P D'OrazioG A Rechnitz
Jun 25, 1979·Nucleic Acids Research·P BaldacciP Kourilsky
Aug 1, 1979·Applied and Environmental Microbiology·F Wasserfall, M Teuber
Dec 1, 1979·Infection and Immunity·G R Germaine, L M Tellefson
Apr 12, 1978·Biochimica Et Biophysica Acta·J M Fernandez-SousaR Rodriguez
Sep 1, 1978·Nucleic Acids Research·A E SippelG Schütz
Mar 17, 1978·Deutsche medizinische Wochenschrift·J Zissu, L Filippini
Feb 1, 1978·Journal of Neurology, Neurosurgery, and Psychiatry·C TaitzB Arensburg
May 1, 1978·The Biochemical Journal·M Z Atassi, C L Lee
Feb 1, 1975·Canadian Journal of Microbiology·W C Trentini, R G Murray
Feb 1, 1975·Journal of Medical Microbiology·R E Wooley, J L Blue
Jan 1, 1977·Preparative Biochemistry·P Bailon, A H Nishikawa
Jan 1, 1976·Journal of Agricultural and Food Chemistry·D C Ting, E E Schrier
Aug 1, 1975·CRC Critical Reviews in Biochemistry·G CareriE Gratton
Feb 20, 1975·The New England Journal of Medicine·K R FalchukK J Isselbacher
Oct 5, 1975·Journal of Molecular Biology·C R BeddellS J Oatley
May 1, 1976·Journal of Agricultural and Food Chemistry·J Kanner, M Karel
Jun 18, 1971·Biochemical and Biophysical Research Communications·A A GalloH Z Sable
Aug 5, 1974·Journal of Molecular Biology·V I TeichbergA Yonath
Apr 18, 1967·Proceedings of the Royal Society of London. Series B, Containing Papers of a Biological Character·J A Rupley
Oct 11, 1974·Biochimica Et Biophysica Acta·S Silberstein, M Inouye
Jun 1, 1972·The Journal of Urology·M C GoldschmidtD E Johnson
Nov 15, 1972·Comparative Biochemistry and Physiology. B, Comparative Biochemistry·D V VadehraH B Naylor
Sep 28, 1972·Journal of Molecular Biology·M NakanishiA Ikegami
Dec 1, 1972·The Biochemical Journal·A R Rees, R E Offord
Apr 25, 1973·Journal of Molecular Biology·M NakanishiA Ikegami
Jan 25, 1974·Journal of Molecular Biology·R Diamond
Jan 25, 1974·Journal of Molecular Biology·M Levitt
May 1, 1968·Journal of Clinical Pathology·J Hawiger
Aug 1, 1969·Science·D M Chipman, N Sharon
Aug 1, 1971·Canadian Journal of Biochemistry·M Bakri, F H Wolfe
May 23, 1972·Biochemistry·C Tanford, R Roxby
Mar 14, 1972·Journal of Molecular Biology·I D Swan
Jul 1, 1971·Poultry Science·F E Cunningham, O J Cotterill
Nov 1, 1968·Journal of Biochemistry·R Sakakibara, K Hamaguchi
Mar 1, 1969·Archives of Biochemistry and Biophysics·L R Gurley, J M Hardin
Mar 1, 1969·Archives of Biochemistry and Biophysics·R M PARRYK M SHAHANI
Apr 10, 1969·Biochemical and Biophysical Research Communications·C C McDonald, W D Phillips
Apr 22, 1969·Biochimica Et Biophysica Acta·R C DaviesB M Wilson
Nov 22, 1965·Biochimica Et Biophysica Acta·R C CHANDANK M SHAHANI
Nov 1, 1967·Poultry Science·F E Cunningham, H Lineweaver
Jul 1, 1983·Journal of Biochemistry·T FukamizoK Hayashi
Jul 1, 1983·Biopolymers·L J BakerW P Bryan
Jan 1, 1980·Applied and Environmental Microbiology·B M Chassy, A Giuffrida
Nov 1, 1981·Biophysical Chemistry·C AbadJ E Figueruelo
Feb 1, 1980·Urology·J D Francis
Mar 1, 1980·Journal of Biochemistry·S KuramitsuK Nakashima
Jul 1, 1980·Journal of Agricultural and Food Chemistry·J FunesM Karel
Mar 1, 1956·Archives of Biochemistry and Biophysics·S EHRENPREIS, R C WARNER
Mar 1, 1956·Archives of Biochemistry and Biophysics·R E FEENEYE D DUCAY
Aug 1, 1956·The Journal of Obstetrics and Gynaecology of the British Empire·E M SCOTT, A M THOMSON
Dec 13, 1963·Biochimica Et Biophysica Acta·J JOLLESP JOLLES
Oct 3, 1964·Nature·R C CHANDANR G HOLLY
Jun 1, 1965·Proceedings of the Society for Experimental Biology and Medicine·R M PARRYK M SHAHANI
Jan 1, 1955·The Journal of Infectious Diseases·R G PETERSON, S E HARTSELL
May 1, 1955·The Biochemical Journal·N L KANTIENGARG A PITT
Apr 22, 1960·Biochimica Et Biophysica Acta·M R SALTON, J G PAVLIK
Sep 1, 1950·Biochimica Et Biophysica Acta·J R HAWTHORNE
May 1, 1952·Journal of Bacteriology·A N SMOLELIS, S E HARTSELL
Nov 1, 1949·Proceedings of the Society for Experimental Biology and Medicine·V ROSS
Aug 1, 1977·Journal of Food Protection·Joseph M Kornfeld


Feb 14, 2012·Applied Biochemistry and Biotechnology·Katia LiburdiMarco Esti
Apr 24, 2010·Journal of Biosciences·Lien Callewaert, Chris W Michiels
Feb 1, 1991·International Journal of Food Microbiology·J M LairdR C McKellar
Apr 6, 2002·International Journal of Food Microbiology·Steeg P F ter, J E Ueckert
Dec 16, 2003·International Journal of Food Microbiology·Jill K Branen, P Michael Davidson
Apr 26, 2013·The Journal of Biological Chemistry·Sophie Réhault-GodbertYves Nys
Nov 13, 2008·Cancer Biotherapy & Radiopharmaceuticals·Ali I GuzelAyfer Pazarbasi
Jan 1, 1992·Society for Applied Bacteriology Symposium Series·G W Gould
Jul 9, 2013·Journal of Pharmacy & Bioallied Sciences·Sathyadevi VenkataramaniDenis R Coleman
Dec 1, 2012·Cellular and Molecular Bioengineering·David M FoureauGloria D Elliott
Mar 1, 2012·Comparative Biochemistry and Physiology. Part B, Biochemistry & Molecular Biology·Chongbo HeXianggang Gao
Jun 12, 2014·Microbiological Research·Michał ArabskiWiesław Kaca
Oct 12, 2010·Journal of Biotechnology·Joris BeldDonald Hilvert
Jul 30, 2010·Ultrasonics Sonochemistry·Sadie DeanJesús Iniesta
Jan 3, 2013·Biotechnology Journal·Barbara ThallingerGeorg M Guebitz
Jul 18, 2006·International Journal of Food Microbiology·Dorothy NakimbugweChris W Michiels
Feb 17, 2006·International Journal of Food Microbiology·Miia LindströmHannu Korkeala
Nov 19, 2015·Asian-Australasian Journal of Animal Sciences·Ming Feng JiangLi Wang
May 28, 2014·Journal of the Science of Food and Agriculture·Maria SelvaggiVincenzo Tufarelli
Aug 15, 2015·Journal of Animal Science and Biotechnology·W T Oliver, J E Wells
Sep 27, 2012·European Journal of Pharmaceutics and Biopharmaceutics : Official Journal of Arbeitsgemeinschaft Für Pharmazeutische Verfahrenstechnik E.V·Sie Huey LeeReginald B H Tan
Jan 17, 2014·Journal of Biotechnology·Huiqing YuGuoxiang Cheng
Apr 13, 2015·Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences·Gulay BayramogluM Yakup Arica
Jun 25, 2016·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Zhipan WuGuozou Cao
Jul 4, 2016·Journal of Photochemistry and Photobiology. B, Biology·K HemalathaMariadhas Valan Arasu
Apr 18, 2014·The Journal of Physical Chemistry. B·Ananta GhimireChalla V Kumar
Sep 25, 2016·Developmental and Comparative Immunology·Felicia Di FalcoAiti Vizzini
Jan 18, 2017·The Journal of Physical Chemistry. B·Anirban Basu, Gopinatha Suresh Kumar
Jul 15, 2015·Scientific Reports·Laura MariñoMiquel Adrover
Feb 21, 2018·Poultry Science·Takashi AkazawaTakahiro Niwa
Jun 9, 2018·Critical Reviews in Food Science and Nutrition·Bilal Muhammad KhanYang Liu
Jul 31, 2016·Applied and Environmental Microbiology·Ewelina WachnickaM W Peck
Mar 26, 2010·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Dinh T TranJeroen Lammertyn
Nov 24, 2007·Journal of Food Science·S NamM S Izydorczyk
Jan 27, 2019·Magnetic Resonance in Chemistry : MRC·Svenja M AckermannMirko Bunzel
Jun 13, 2013·Journal of the American College of Nutrition·Filippo RossiGeltrude Mingrone
May 20, 2014·Journal of Food Science·Ladan AminlariMahmoud Aminlari
Apr 8, 2011·Macromolecular Bioscience·Dhriti NepalSatish Kumar
Mar 8, 2017·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Heng LiZhengqiang Li
Jun 4, 2002·The Journal of Nutrition·Brooke D HumphreyKirk C Klasing
Nov 23, 2005·Journal of Food Protection·Seacheol MinJohn M Krochta
Jul 22, 2010·Pharmaceutical Biology·Débora da Silva Freitas, José Abrahão-Neto
Nov 7, 2019·International Journal of Molecular Sciences·Alberta BergamoGianni Sava
Nov 9, 2019·International Journal of Molecular Sciences·Edward J TaylorKeith S Wilson
Mar 15, 2020·International Journal of Molecular Sciences·Xingquan PanJunhai Xiao
Aug 23, 2020·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Shinji KatsuraEtsuo Yonemochi
Jun 30, 2018·International Journal of Food Science·Ahmad Ni'matullah Al-BaarriShigeru Hayakawa
Mar 22, 2020·Scientific Reports·Sungmun LeeTae-Yeon Kim

Related Concepts

Enzyme Stability
Food Preservatives
Tears Body Substance

Related Feeds

Bacterial Cell Wall Structure (ASM)

Bacterial cell walls are made of peptidoglycan (also called murein), which is made from polysaccharide chains cross-linked by unusual peptides containing D-amino acids. Here is the latest research on bacterial cell wall structures.


Antiparasitics are medications which are indicated for the treatment of parasitic diseases. Discover the latest research on antiparasitics here.

Bacterial Cell Wall Structure

Bacterial cell walls are made of peptidoglycan (also called murein), which is made from polysaccharide chains cross-linked by unusual peptides containing D-amino acids. Here is the latest research on bacterial cell wall structures.