PMID: 9422249Sep 1, 1995Paper

The Chiari malformations: a constellation of anomalies

Seminars in Pediatric Neurology
R M Shuman

Abstract

The Chiari malformations form a group of abnormalities that are pathogenetically interrelated. The most important member of the group is the Chiari type II malformation, known as the Arnold-Chiari malformation. Its cardinal features are the myelomeningocele in the thoraco-lumbar spine, the venting of the intracranial cerebrospinal fluid through the central canal, the hypoplasia of the posterior fossa, the herniation of hindbrain into the cervical spinal canal, and the compressive damage to cranial nerves. Some of the abnormalities are progressive, and thus treatable. Limitation of progression may improve outcomes. The challenges to our treatment programs involve early diagnosis, delivery by Caesarean section, emergent closure of the neural plaque and prophylaxis of hydrocephalus, anticipatory prevention of the neurological compression syndromes, multidisciplinary teams, and age-appropriate interventions.

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Citations

Nov 21, 2007·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·Elka MillerCharles Raybaud
Apr 24, 2010·Child's Nervous System : ChNS : Official Journal of the International Society for Pediatric Neurosurgery·Amir ZolalMartin Sames
Sep 22, 2001·European Journal of Radiology·A SirikciM Bayram
Jun 13, 2008·Otolaryngologia polska. The Polish otolaryngology·A PruszewiczJ Jackowska
Mar 2, 2012·Journal of Child Neurology·Valentina CittonRenzo Manara
May 2, 2003·The British Journal of Psychiatry : the Journal of Mental Science·Peter J CooperHelena Romaniuk
Oct 7, 2021·Pediatric and Developmental Pathology : the Official Journal of the Society for Pediatric Pathology and the Paediatric Pathology Society·Fabienne PaschereitAngela M Kaindl

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