The ChromaTest, a digital color contrast sensitivity analyzer, for diabetic maculopathy: a pilot study.

BMC Ophthalmology
Roger WongVictor Chong

Abstract

To assess the ability of the Chromatest in investigating diabetic maculopathy. Patients with Type 2 diabetes and no concurrent ocular pathology or previous laser photocoagulation were recruited. Visual acuities were assessed followed by colour contrast sensitivity testing of each eye using Chromatest. Dilated fundoscopy with slit lamp biomicroscopy with 78 D lens was then performed to confirm the stage of diabetic retinopathy according to the Early Treatment Diabetic Retinopathy Study. 150 eyes in 150 patients were recruited into this study. 35 eyes with no previous laser photocoagulation were shown to have clinically significant macular oedema (CSMO) and 115 eyes with untreated non-proliferative diabetic retinopathy (NPDR) on fundus biomicroscopy. Statistical significant difference was found between CSMO and NPDR eyes for protan colour contrast threshold (p = 0.01). Statistical significance was found between CSMO and NPDR eyes for tritan colour contrast threshold (p = 0.0002). Sensitivity and specificity for screening of CSMO using pass-fail criterion for age matched TCCT results achieved 71% (95% confidence interval: 53-85%) and 70% (95% confidence interval: 60-78%), respectively. However, threshold levels were derived using ...Continue Reading

Associated Clinical Trials

References

Apr 15, 1992·Annals of Internal Medicine·D E SingerA P Schachat
Nov 11, 1989·BMJ : British Medical Journal·T E RohanN J Wald
Jun 1, 1988·Documenta Ophthalmologica. Advances in Ophthalmology·G ArdenS Perry
Sep 1, 1985·Archives of Ophthalmology·G H BresnickS Syrjala
May 1, 1982·American Journal of Ophthalmology·G VerriestA Uvijls
Jun 18, 1982·JAMA : the Journal of the American Medical Association·E J SussmanK A Soper
May 1, 1994·International Journal of Psychophysiology : Official Journal of the International Organization of Psychophysiology·S J TregearJ P Reffin
Dec 28, 1999·Endocrinology and Metabolism Clinics of North America·S Caprio, W V Tamborlane
Oct 3, 2002·Diabetic Medicine : a Journal of the British Diabetic Association·G P LeeseA Ellingford
Jan 27, 2004·Canadian Journal of Ophthalmology. Journal Canadien D'ophtalmologie·Marie Carole BoucherSébastien Olivier
Jan 25, 2006·Telemedicine Journal and E-health : the Official Journal of the American Telemedicine Association·John D WhitedSven-Erik Bursell
Jul 14, 2007·The British Journal of Ophthalmology·E Olafsdóttir, E Stefánsson
Oct 27, 2007·Investigative Ophthalmology & Visual Science·Gianni VirgiliRaffaella Gortana Chiodini

❮ Previous
Next ❯

Citations

Oct 5, 2010·Ophthalmic & Physiological Optics : the Journal of the British College of Ophthalmic Opticians (Optometrists)·M O'Neill-BibaJ L Barbur
Oct 27, 2015·Current Diabetes Reports·David J Ramsey, G B Arden
Mar 7, 2015·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Hongting LiuQuan Dong Nguyen
Sep 23, 2014·Translational Vision Science & Technology·Hongting LiuQuan Dong Nguyen
Mar 6, 2021·NPJ Primary Care Respiratory Medicine·Sunita ChannaAlice M Turner

❮ Previous
Next ❯

Software Mentioned

Chromatest
The

Related Concepts

Related Feeds

Birth Defects

Birth defects encompass structural and functional alterations that occur during embryonic or fetal development and are present since birth. The cause may be genetic, environmental or unknown and can result in physical and/or mental impairment. Here is the latest research on birth defects.