PMID: 8590467Jul 1, 1995Paper

The chromosomal region which includes the recombinator cog in Neurospora crassa is highly polymorphic

Current Genetics
P Jane Yeadon, David Catcheside

Abstract

The St Lawrence ST74-OR23-IVA and Lindegren Y8743 strains of Neurospora crassa have a different provenance from wild collections and dissimilar cog alleles; that in Lindegren, cogLa (previously designated cog+), is a more efficient recombinator than cogS74A and cogEa (previously cog), the alleles in St Lawrence and Emerson a respectively. Restriction fragment length polymorphisms (RFLPs) and sequence polymorphisms (SPs) were used to map the difference between cogLa and cogS74A to a region that extends from 2.3 to 3.2 kb 3' of the his-3 coding sequence. The DNA sequences from 400 bp 3' of his-3 to 120 bp 3' of the cog region in these strains were found to be homologous but to diverge by 3.5%. The differences include single-base pair changes, short insertion/deletions, differences in the length of poly-T tracts, and three longer sequences present only in St Lawrence: a 98-bp inverted repeat transposable element we have previously called Guest, which has generated a 3-bp direct repeat of the target site present in Lindegren, and 15-bp and 20-bp sequences that have no obvious structural features nor similarity to Guest. Southern analysis of other laboratory strains revealed four major and several minor variants of this region. All ...Continue Reading

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Citations

Mar 29, 2001·Fungal Genetics and Biology : FG & B·D D Perkins, R H Davis
Apr 10, 1995·Molecular & General Genetics : MGG·P J Yeadon, D E Catcheside
Dec 29, 2011·Molecular Genetics and Genomics : MGG·P J YeadonD E A Catcheside
Jun 27, 2013·Molecular Genetics and Genomics : MGG·F J BowringD E A Catcheside
Jun 5, 2003·Fungal Genetics and Biology : FG & B·Barbara C Turner
Jan 19, 2002·Plasmid·J Paul RasmussenDavid E A Catcheside
Jun 1, 1997·Fungal Genetics and Biology : FG & B·A Radford, J H Parish
Feb 25, 1998·Genetics·P J Yeadon, D E Catcheside

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