The chronic effects of dietary lead in freshwater juvenile rainbow trout (Oncorhynchus mykiss) fed elevated calcium diets

Aquatic Toxicology
L C Alves, Chris M Wood

Abstract

This study examined the impact of elevated dietary Ca(2+) on the responses to chronic dietary Pb exposure in juvenile rainbow trout. Trout were fed reference (0.3microgPb/g, approximately 20mgCa(2+)/g) and Pb-enriched diets ( approximately 50 or 500microgPb/g) in the presence of background Ca(2+) ( approximately 20mgCa(2+)/g) or ( approximately 60mgCa(2+)/g) of added Ca(2+) (as CaCO(3)) for 42 days. The quantitative order of Pb accumulation in tissues reflected the exposure pathway of Pb via the diet (per tissue wet weight): gut>bone>kidney>liver>spleen>gill>carcass>brain>white muscle. The anterior intestine accumulated the most Pb per tissue wet weight, while the bone accumulated the most Pb per fish weight. Pb concentrations were much higher in the posterior kidney than the anterior kidney. Simultaneous addition of Ca(2+) to the diet had an overall protective effect in all the tissues analysed in reducing Pb accumulation. The RBCs accumulated 100 times more Pb when compared to the plasma, while the whole blood delta-aminolevulinic acid dehydratase was inhibited in the high treatment group without added Ca(2+), by the end of the exposure. Neither plasma Cl(-), K(+), Mg(2+) nor Na(+), K(+)-ATPase activities in the gills, mid- a...Continue Reading

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Citations

Oct 12, 2012·Environmental Science and Pollution Research International·Ewa Łuszczek-TrojnarWłodzimierz Popek
Oct 12, 2013·Fish Physiology and Biochemistry·Andrea Martini RibeiroClaudia B R Martinez
Jul 9, 2009·Comparative Biochemistry and Physiology. Toxicology & Pharmacology : CBP·Raymond W M Kwong, Som Niyogi
Feb 10, 2007·Comparative Biochemistry and Physiology. Toxicology & Pharmacology : CBP·Gülüzar Atli, Mustafa Canli
Mar 29, 2011·Environmental Toxicology and Chemistry·Martín F Soto-JiménezFederico Páez-Osuna
Sep 8, 2010·Environmental Toxicology and Chemistry·David BoyleNic R Bury
Nov 9, 2014·Environmental Science and Pollution Research International·Yousef S Saleh, Mohamed-Assem S Marie
Jul 28, 2016·The Science of the Total Environment·Luciana Fernandes de OliveiraClaudia Bueno Dos Reis Martinez
Mar 13, 2018·Environmental Toxicology and Chemistry·Luciana Fernandes de OliveiraClaudia Bueno Dos Reis Martinez
Jan 28, 2020·Critical Reviews in Food Science and Nutrition·Karolina KwasekMichael Phillips
Jun 6, 2021·Aquatic Toxicology·Angélica Alves de PaulaClaudia Bueno Dos Reis Martinez
Aug 5, 2021·Chemosphere·Maiara VicentiniHelena Cristina Silva de Assis
Jan 22, 2020·Comparative Biochemistry and Physiology. Part A, Molecular & Integrative Physiology·Jéssica Fernanda Bernardes RodaClaudia Bueno Dos Reis Martinez

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