Apr 1, 1976

The chronotropic effect of maximal stress on the heart and its regulation

Fiziologicheskiĭ zhurnal SSSR imeni I. M. Sechenova
M G Pshennikova


The reflex bradycardia occurring at the maximal isometric heart strain produced by clamping of aorta was shown to be less intense if the heart rate prior to the experiment had been low. Vagotomy prevented or decreased the bradycardia. The beta-adrenoreceptor blockade with inderal significantly reduced the bradycardia, whereas the alpha-adrenoreceptor blockade with tropaphen increased it. The important role of relationship between adrenergic and cholinergic regulation of the heart in development of the bradycardia was discussed.

  • References
  • Citations


  • We're still populating references for this paper, please check back later.
  • References
  • Citations


  • This paper may not have been cited yet.

Mentioned in this Paper

Sympathetic Nervous System
Reflex Bradycardia
Norepinephrine, (+, -)-Isomer
Adrenergic alpha-Antagonists
Vagus Nerve Structure
Clamping Activity
Entire Aorta
Adrenergic Receptor

About this Paper

Related Feeds


Bradyarrhythmias are slow heart rates. Symptoms may include syncope, dizziness, fatigure, shortness of breath, and chest pains. Find the latest research on bradyarrhythmias here.

Adrenergic Receptors: Trafficking

Adrenergic receptor trafficking is an active physiological process where adrenergic receptors are relocated from one region of the cell to another or from one type of cell to another. Discover the latest research on adrenergic receptor trafficking here.