PMID: 26815343Jan 28, 2016Paper

The clinical and bacterial features of Klebsiella pnuemoniae liver abscess

Zhonghua yi xue za zhi
Hua WuDingxia Shen

Abstract

To summarize the clinical and bacterial features of Klebsiella pnuemoniae liver abscess (KPLA) in order to provide the basis for the diagnosis and treatment of KPLA. Retrospective study was conducted. One hundred and fifty-two medical records, from 3 teaching hospitals in Beijing, between January 2010 and December 2014, were collected. Among which 137 complete medical records were analyzed. String test was carried out to detect the hypermucoviscosity phenotype. PCR was performed to check the capsular serotype and the virulent genes. Disk diffusion method was operated to obtain the antimicrobial resistance rates. The results were analyzed by chi-square test. KPLA occurred mostly in middle-aged, male and diabetes mellitus patients. 92.7% (127/137) patients had fever. 80.3% (110/137) of the KLPA were single abscess, among which 80.9% (89/110) were in the right lobe and 33.6% (46/137) had air cavities.74.5% (102/137) of the white blood cell count, 83.2% (114/137) of the neutrophils' percentage, 78.1% (107/137) of alanine aminotransferase and 51.8% (71/137) of the total billrubin were elevated. 87.5% (133/152) of the Klebsiella pnuemoniae (Kpn) appeared to be hypermucoviscous, K1 was the most popular serotype, the second was K2, and...Continue Reading

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