Abstract
The proper assessment of the current disease status of patients with chronic hepatitis B would be valuable for establishing optimal management strategies. The clinical and laboratory characteristics of 2,954 patients with current or previous antiviral treatment (46.2±10.8 years, 69.7% male) enrolled from 46 referral hospitals and 129 local hospitals or clinics throughout Korea were analyzed. The disease status included chronic hepatitis, cirrhosis, and hepatocellular carcinoma in 79.9%, 16.4%, and 3.7% of the patients, respectively. The major mode of hepatitis B virus (HBV) infection was vertical transmission. The hepatitis C virus (HCV) co-infection rate was 1.5%; however, only 50.8% of patients were evaluated for HCV. The use of herbal or complementary medicines was reported in 33.5% of the patients. The majority of patients (97.6%) were treated with oral nucleoside/nucleotide analogues. Several characteristics were different between the patients treated at referral hospitals and local hospitals/clinics, including the disease state, choice of antiviral drug, and methods of HBV DNA measurement. This study provides a comprehensive picture of the clinical and laboratory characteristics of patients treated in Korea. Efforts to op...Continue Reading
References
Mar 1, 1990·Vaccine·J L Sung
May 29, 1998·International Journal of Epidemiology·M S LeeY O Ahn
Oct 5, 2001·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·S J Hadziyannis, D Vassilopoulos
May 23, 2002·Gastroenterology·Jean-Michel Pawlotsky
Aug 13, 2002·Journal of Korean Medical Science·Duk-Hee LeeHai-Rim Shin
Mar 5, 2004·Journal of Viral Hepatitis·D Lavanchy
Dec 24, 2005·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Snorri S Thorgeirsson, Joe W Grisham
Feb 1, 2006·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Hyung Joon Yim, Anna Suk-Fong Lok
Feb 16, 2006·Journal of Korean Medical Science·Bo-Moon ShinSang Keun Park
Aug 31, 2006·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Hyung Joon YimAnna S F Lok
Jan 30, 2007·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Anna S F Lok, Brian J McMahon
Jul 24, 2008·Journal of Medical Virology·Haesun YunYoungmee Jee
Dec 5, 2008·Journal of Hepatology·UNKNOWN European Association For The Study Of The Liver
Dec 6, 2008·The Korean Journal of Hepatology·Kwan Sik LeeUNKNOWN Korean Association for the Study of the Liver Guideline Committee
Aug 29, 2009·Hepatology : Official Journal of the American Association for the Study of Liver Diseases·Anna S F Lok, Brian J McMahon
Sep 29, 2009·The Korean Journal of Hepatology·UNKNOWN Korean Liver Cancer Study Group and National Cancer Center, Korea
Apr 7, 2010·The Korean Journal of Hepatology·Hee Bok ChaeHyung Joon Yim
May 19, 2010·Gut and Liver·Moon Seok Choi, Byung Chul Yoo
Sep 8, 2010·Annals of Hematology·Jun KangJooryung Huh
Oct 23, 2010·European Journal of Gastroenterology & Hepatology·Patrick MarcellinJean-Pierre Zarski
Jul 16, 2011·The Korean Journal of Hepatology·So Young Kwon, Chang Hong Lee
Citations
Mar 29, 2013·PloS One·Jun Yong ParkMyung Seok Lee
Nov 6, 2014·PloS One·Dong Hyun SinnByung Chul Yoo
Oct 3, 2013·Asian Pacific Journal of Tropical Medicine·Xiu-Li XuXiao-Ke Hao
Jul 16, 2019·Zoonoses and Public Health·Nasrin Shirmohammadi-KhorramZohreh Maryanaji
Jun 13, 2019·Clinical and Molecular Hepatology·UNKNOWN Korean Association for the Study of the Liver (KASL)
Sep 26, 2017·Clinical and Molecular Hepatology·Dong Hyun SinnMoon Seok Choi