The clinical biochemistry of aluminum

Critical Reviews in Clinical Laboratory Sciences
S W KingM R Wills

Abstract

The methods for aluminum analysis vary from the simple and often nonspecific chemical and physical procedures to the highly sophisticated types such as neutron activation and atomic absorption spectrometry. Atomic absorption procedures are the techniques of choice for most routine hospital laboratories. The wide distribution of aluminum in nature can create severe contamination problems in aluminum analysis. Procedures to avoid contamination are discussed. In recent years aluminum has been implicated as a possible etiological agent in DES and in Alzheimer's Disease. A common finding in these two conditions is an elevated brain aluminum content. The patients with Alzheimer's Disease develop characteristic neurofibrillary tangles which lead to the degeneration of the affected neurons. Similar tangles can be induced in laboratory animals injected intracerebrally with aluminum salts. Even though the laboratory animals develop tangles resembling those seen in patients with Alzheimer's Disease, no evidence has been published to show that the tangles seen in Alzheimer's Disease are induced by the elevated brain aluminum content. Although there are some similar clinical symptoms in both Alzheimer's Disease and DES, the hemodialysis pat...Continue Reading

References

Jun 5, 1976·Lancet·J A FlendrigH A Das
Apr 29, 1978·Lancet·J R McDermottD N Kerr
Oct 28, 1978·Lancet·H L ElliottG S Fell
Dec 9, 1978·Lancet·H L ElliottP H Gardiner
Feb 17, 1979·Lancet·H GrafW F Pinggera
Oct 13, 1979·Lancet·G Cournot-WitmerS Balsan
Oct 1, 1979·Proceedings of the National Academy of Sciences of the United States of America·F C Womack, S P Colowick
Sep 17, 1977·British Medical Journal·P SullivanN Callaghan
Jan 1, 1978·Annual Review of Medicine·A C Alfrey
May 1, 1979·Annals of Internal Medicine·A I ArieffV C Lazarowitz
Nov 1, 1979·Hypertension·W R HarlanP E Leaverton
Mar 1, 1979·Neurology·W D SniderJ D Mann
Nov 1, 1977·Kidney International·W D KaehnyW J Shorr
Apr 1, 1978·Annals of Internal Medicine·G DuneaE C Smith
Apr 29, 1978·British Medical Journal·H L ElliottA I Macdougall
Apr 1, 1978·Kidney International·S D MahurkarG Dunea
Jan 1, 1978·Canadian Psychiatric Association Journal·D R Crapper, U DeBoni
Sep 1, 1978·Archives of Internal Medicine·V V RozasW M Rutt
Jan 1, 1978·Age and Ageing·P W OverstallA N Exton-Smith
Dec 9, 1978·British Medical Journal·M PoissonB Lebkiri
Jan 1, 1978·Journal of Dialysis·S D MahurkarG Dunea
Mar 1, 1976·Brain : a Journal of Neurology·D R CrapperS Quittkat
Oct 1, 1976·Clinical Science and Molecular Medicine·J M CamH E de Wardener
Dec 1, 1976·Neurology·A M Nadel, W P Wilson
Feb 1, 1975·Australian and New Zealand Journal of Medicine·L J Barratt, J R Lawrence
Jan 22, 1976·The New England Journal of Medicine·A C AlfreyW D Kaehny
Jun 1, 1976·Analytical Chemistry·A J BlotckyR R Recker
Mar 11, 1972·Lancet·G M BerlyneG M Danovitch
Jun 23, 1973·Lancet·S D MahurkarG Dunea
Jul 7, 1973·Lancet·E N Wardle
Jun 26, 1974·Histochemistry·U De BoniD R Crapper
Sep 5, 1970·Lancet·G M BerlyneG R Gilmore
Jan 1, 1972·Transactions - American Society for Artificial Internal Organs·A C AlfreyJ H Holmes
Mar 23, 1974·British Medical Journal·C E Dent, C S Winter
Jul 20, 1974·British Medical Journal·L R BakerL Watson
Oct 30, 1971·British Medical Journal·V ParsonsJ Siddiqui

❮ Previous
Next ❯

Citations

Nov 1, 1987·Proceedings of the National Academy of Sciences of the United States of America·J Fleming, J G Joshi
Jun 1, 1988·The Journal of Clinical Investigation·J Mladenovic
Dec 24, 1997·Critical Reviews in Clinical Laboratory Sciences·J L Greger, J E Sutherland
Jan 1, 1989·Journal of Toxicology. Clinical Toxicology·J L Domingo
Jan 10, 2002·Journal of Toxicology. Clinical Toxicology·W Zheng
May 1, 1988·The American Journal of the Medical Sciences·W A Banks, A J Kastin
Nov 1, 1985·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·M Burnatowska-Hledin, G H Mayor
Nov 1, 1985·American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation·T L Petit
Jul 23, 2013·Journal of Trace Elements in Medicine and Biology : Organ of the Society for Minerals and Trace Elements (GMS)·Cristinel N DegeratuDaniel Chappard
Feb 1, 1985·Toxicology and Applied Pharmacology·R A Yokel, P J McNamara
Jan 1, 1987·International Endodontic Journal·S Meryon, J Jakeman
Jan 1, 1989·Neuroscience and Biobehavioral Reviews·W A Banks, A J Kastin
Apr 1, 1984·Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association·A LioneJ C Smith
Mar 1, 1988·JPEN. Journal of Parenteral and Enteral Nutrition·W W KooS K Krug-Wispe
Nov 1, 1986·JPEN. Journal of Parenteral and Enteral Nutrition·W W KooJ J Steichen
Dec 1, 1982·Biological Trace Element Research·J L GregerM J Baier
Aug 1, 1988·Pediatric Dermatology·L SirotaM Djaldetti
Dec 1, 1983·Biological Trace Element Research·R A Yokel
Sep 1, 1985·Biomedical Mass Spectrometry·A H VerbuekenR E Van Grieken
Jan 1, 1987·Critical Reviews in Clinical Laboratory Sciences·A H VerbuekenR Van Grieken
Mar 1, 1990·Environmental Geochemistry and Health·S G Epstein
Mar 1, 1990·Environmental Geochemistry and Health·G F Craun
Oct 1, 1987·Acta Orthopaedica Scandinavica·T Albrektsson, B Albrektsson
Jun 1, 1988·Journal of the American College of Nutrition·W W Koo, L A Kaplan
Aug 17, 1994·Molecular and Cellular Biochemistry·K S Rao, G V Rao
Mar 27, 2007·Journal of Biomedical Materials Research. Part B, Applied Biomaterials·Keun-Taek OhKyoung-Nam Kim
Jan 1, 1984·Critical Reviews in Toxicology·G L KruegerE M Widner
Sep 1, 1992·Advances in Dental Research·R L Bowen, W A Marjenhoff
Dec 4, 2016·International Journal of Toxicology·Lillian C BeckerF Alan Andersen
Mar 25, 2020·Interdisciplinary Toxicology·Ikechukwu Onyebuchi IgbokweNanacha Afifi Igbokwe
Aug 1, 1983·Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association·J L Greger, M J Baier
Nov 1, 1988·Mutation Research·A Léonard, G B Gerber
Dec 1, 1986·Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association·J L Greger, S E Donnaubauer
Jan 1, 1985·Pharmacology & Therapeutics·A Lione
Oct 1, 1993·Comparative Biochemistry and Physiology. C, Comparative Pharmacology and Toxicology·K ZamanJ Batcabe
Jan 1, 1985·Psychoneuroendocrinology·W A Banks, A J Kastin
Apr 1, 1987·Archives of Biochemistry and Biophysics·C Weis, A Haug
Feb 18, 2014·ACS Applied Materials & Interfaces·Jungmok YouEunkyoung Kim

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