The clinical effect of an unloader brace on patients with osteoarthritis of the knee, a randomized placebo controlled trial with one year follow up

BMC Musculoskeletal Disorders
Hjörtur F Hjartarson, Sören Toksvig-Larsen

Abstract

Treatment of patients with knee osteoarthritis is challenging. Unloader braces have been developed with various success. Unloader One® Knee Brace is light, easily-fitted and shown to be effective by the unloading of the affected compartment. The aim of the study was to assess the clinical outcome of the brace vs. a placebo on patients with knee osteoarthritis. Initially 150 patients were randomized to receive either the Unloader brace or a control placebo group look-alike brace where the active strips had been removed. The patients were followed up at 6,12,26 and 52 weeks with Knee Society Score (KSS) and Knee injury and Osteoarthritis Outcome Score (KOOS). The reason for dropout was recorded. A total of 149 patients were included, 74 in the study and 75 in the control group. The mean age was 59.6 vs. 60.2, BMI was 27.5 vs. 26.9, 37% vs. 44% were women in the study vs. control group. Both groups showed improvement in KSS over 52 weeks, with the study group showing higher improvement in mean scores. KSS increased from 64.3 to 84.0 for the study group and from 64.0 to 74.6 for the control group (p = 0.009). The study group improved in KSS function from 67.0 to 78.6 (p < 0.001) and KOOS for knee related symptoms increased/improved...Continue Reading

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References

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Citations

Jun 7, 2019·Biomedical Engineering Letters·Rizuwana ParweenKarupppasamy Subburaj
Nov 7, 2019·Orthopaedic Journal of Sports Medicine·Katherine MarinoPaul Lee
Oct 8, 2020·Knee Surgery, Sports Traumatology, Arthroscopy : Official Journal of the ESSKA·Jaclyn A KonopkaJason L Dragoo
Jan 29, 2021·Assistive Technology : the Official Journal of RESNA·Mobina KhosraviMaryam Jalali
Jun 8, 2021·Journal of the American Academy of Orthopaedic Surgeons. Global Research & Reviews·Bernard P KemkerGregory Golladay

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