The clinical implications of tests confirming COPD in subjects hospitalized with exacerbations

Hospital Practice
Chan Yeu PuAiman Tulaimat

Abstract

The diagnosis of COPD in patients hospitalized for AECOPD can be confirmed by spirometry showing obstruction or radiographs showing emphysema. The evidence for COPD is sometimes absent or contradicts this diagnosis. The inaccurate attribution of the exacerbation to COPD can lead to suboptimal care and worse outcome. We determined if the presence of tests that confirm the diagnosis of COPD has any implications on the course of the hospitalization and readmission rate. We selected subjects hospitalized between 2012 and 2014 for AECOPD. We divided them into four hierarchical, mutually exclusive groups based on the presence of tests that confirm the diagnosis of COPD: spirometry (COPDSPIRO), radiology (COPDRAD), clinical diagnosis (COPDCLIN), and no COPD by spirometry (NotCOPD). We compared the presentation, hospital course, outcome, and readmission rate between the four groups. We identified 974 subjects: COPDSPIRO 22%, COPDRAD 24%, COPDCLIN 46% and 7% NotCOPD. The vital signs, use of respiratory support, admission to the MICU, and length of stay were similar between the groups. The age, gender, BMI, presence of comorbidities, and readmission rate were different between the groups. The NotCOPD group had the highest BMI (38 kg/m2),...Continue Reading

References

May 28, 2003·Archives of Internal Medicine·Susheel P PatilGregory B Diette
Feb 2, 2006·The Journal of Asthma : Official Journal of the Association for the Care of Asthma·David G TinkelmanR J Halbert
Jun 17, 2006·Chest·Todd A LeeKevin B Weiss
Jan 16, 2007·Journal of the American College of Cardiology·Thierry H Le JemtelSanja Jelic
Jun 7, 2007·Chest·Meilan K HanFernando J Martinez
Mar 19, 2008·Chest·Min J JooKevin B Weiss
Apr 3, 2009·The New England Journal of Medicine·Stephen F JencksEric A Coleman
Nov 12, 2009·Chest·Raffaele Antonelli IncalziUNKNOWN Extrapulmonary Consequences of COPD in the Elderly Study Investigators
Jun 19, 2010·American Journal of Respiratory and Critical Care Medicine·Ciro CasanovaBartolomé R Celli
Oct 27, 2011·JAMA : the Journal of the American Medical Association·Onno M MetsPim A de Jong
May 9, 2012·Journal of Intensive Care Medicine·Paul E Marik, Himanshu Desai
Jul 13, 2013·International Journal of Chronic Obstructive Pulmonary Disease·Javier de Miguel DíezRodrigo Jiménez García
Dec 19, 2013·International Journal of Chronic Obstructive Pulmonary Disease·Christian GhattasMagdi H Awad
Jan 28, 2014·American Journal of Respiratory and Critical Care Medicine·Laura C Feemster, David H Au
Sep 6, 2014·American Journal of Respiratory and Critical Care Medicine·Valentin Prieto-CenturionUNKNOWN CONCERT Consortium
Nov 3, 2015·Annals of the American Thoracic Society·Carlos H MartinezAlejandro A Diaz
Jan 17, 2017·Chest·Huimin WuAnn E Medinger

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