The clinical relationship between cognitive impairment and psychosocial functioning in major depressive disorder: A systematic review

Psychiatry Research
Olivia R CambridgeBernhard T Baune

Abstract

Cognitive deficits are frequently observed in major depressive disorder (MDD), as well as impaired long-term psychosocial functioning. However, the relationship between cognitive deficits and psychosocial functioning in MDD is under-investigated. We aim to systematically review the literature on the relationship between specific cognitive impairments and psychosocial functioning in MDD. We systematically reviewed English-language literature in PubMed, PsychINFO, Scopus and Web of Science using search terms related to psychosocial functioning. Additional studies were identified by searching reference lists. Following our inclusion/exclusion criteria, 28 studies were reviewed. Inclusion criteria included age (> 18), MDD diagnosed by standard tools (e.g., DSM-IV), use of cognitive and psychosocial assessments. Cross-sectional studies indicated that cognitive deficits in domains of executive functioning, attention, memory, and global cognition are associated with psychosocial dysfunction in domains of as quality of life, and social, occupational, and global functioning. The cognition-functioning relationship was also observed in longitudinal studies, showing that only specific cognitive domains affected psychosocial outcomes over t...Continue Reading

Citations

Sep 14, 2018·Depression and Anxiety·Matthew J Knight, Bernhard T Baune
Apr 26, 2019·Expert Review of Neurotherapeutics·Matthew J KnightBernhard T Baune
Apr 16, 2020·Expert Review of Neurotherapeutics·Thomas BebloLorenz Dehn
Jun 2, 2020·Psychological Medicine·Muriel Vicent-GilNarcís Cardoner
Jan 9, 2020·Harvard Review of Psychiatry·Meghan Vinograd, Michelle G Craske
Mar 20, 2020·Current Pharmaceutical Design·Vicent Balanzá-MartínezPilar López-García
Sep 19, 2019·Applied Neuropsychology. Adult·Laura Damiani BrancoRochele Paz Fonseca
Nov 14, 2018·Frontiers in Psychiatry·Matthew J Knight, Bernhard T Baune
Sep 25, 2020·Journal of Affective Disorders·Jeffrey R VittenglRobin B Jarrett
Aug 1, 2020·Journal of Affective Disorders·Bjørn Ingulfsvann HagenJan Stubberud
Mar 2, 2021·Der Nervenarzt·Thomas M SchillingSteffen Aschenbrenner
Dec 16, 2019·Comprehensive Psychiatry·Matthew J KnightBernhard T Baune
Jul 19, 2021·Psychiatry Research. Neuroimaging·Gereon Johannes SchnellbächerMikhail Votinov
Jul 23, 2021·Progress in Neuro-psychopharmacology & Biological Psychiatry·Yong-Ku Kim
Jul 15, 2021·Archives of Clinical Neuropsychology : the Official Journal of the National Academy of Neuropsychologists·Robson ZazulaSandra Odebrecht Vargas Nunes
Sep 16, 2021·Applied Neuropsychology. Adult·Bjørn Ingulfsvann HagenJan Stubberud
Oct 27, 2021·European Archives of Psychiatry and Clinical Neuroscience·Sara PolettiFrancesco Benedetti

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