The clinical relevance of the clopidogrel-proton pump inhibitor interaction.

Journal of Cardiovascular Translational Research
Atif MohammadSubhash Banerjee

Abstract

Proton pump inhibitors are often prescribed concomitantly with clopidogrel and aspirin to patients post-percutaneous coronary interventions and/or an acute coronary syndrome to mitigate the risk of potential gastrointestinal bleeding, associated primarily with clopidogrel use. Over the last several years, there have been data both supporting and refuting a clopidogrel-proton pump inhibitor interaction. This review critically considers the current evidence and provides practical recommendations to healthcare providers.

References

Dec 25, 2008·The New England Journal of Medicine·Jessica L MegaMarc S Sabatine
Jan 30, 2009·CMAJ : Canadian Medical Association Journal = Journal De L'Association Medicale Canadienne·David N JuurlinkMuhammad M Mamdani
Mar 5, 2009·JAMA : the Journal of the American Medical Association·P Michael HoJohn S Rumsfeld
Apr 8, 2009·Thrombosis and Haemostasis·Dirk SibbingNicolas von Beckerath
Aug 27, 2009·JAMA : the Journal of the American Medical Association·Alan R ShuldinerPaul A Gurbel
Nov 12, 2009·The American Journal of Gastroenterology·Loren Laine, Charles Hennekens
Feb 4, 2010·Cleveland Clinic Journal of Medicine·Jeremiah P Depta, Deepak L Bhatt
Mar 17, 2010·Annals of Internal Medicine·Wayne A RayC Michael Stein
Apr 28, 2010·Archives of Internal Medicine·Karen M StocklScott Ramsey
Oct 12, 2010·The New England Journal of Medicine·Deepak L BhattUNKNOWN COGENT Investigators
Dec 18, 2010·Journal of Cardiovascular Pharmacology·Juan Francisco Sánchez Muñoz-TorreroUNKNOWN Factores de Riesgo y ENfermedad Arterial (FRENA) Investigators
Dec 21, 2010·Nature Reviews. Cardiology·Paul A Gurbel, Udaya S Tantry
Jan 19, 2011·Cardiovascular Revascularization Medicine : Including Molecular Interventions·Ron Waksman
Jan 21, 2011·The American Journal of Cardiology·Subhash BanerjeeDeepak L Bhatt
Mar 12, 2011·Journal of the American College of Cardiology·Eric R BatesDominick J Angiolillo
Apr 28, 2011·Circulation. Cardiovascular Interventions·José Luis FerreiroDominick J Angiolillo

❮ Previous
Next ❯

Citations

Feb 26, 2014·Journal of Cardiovascular Translational Research·Salvatore Patanè
Jul 22, 2018·European Journal of Gastroenterology & Hepatology·Md Mohaimenul IslamYu-Chuan Jack Li

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.