The clinical use of the 10g monofilament and its limitations: a review

Diabetes Research and Clinical Practice
Liang S Tan

Abstract

Diabetes mellitus is one of the most prevalent chronic diseases worldwide including Singapore. The 10g monofilament is commonly used by clinicians to examine diabetic patients for neuropathy due to its low cost and convenience. The aim of this literature review is to evaluate the use of the monofilament and the factors that affect its diagnostic value. A systematic search of AMED, Medline, EMBASE and Cinahl databases was conducted to identify English language articles from 1990 to 2009 which investigated the use of the monofilament. A total of 34 studies were identified, consisting of 24 observational studies, 8 prospective studies, 1 review article and 1 randomised controlled trial. 6 recurrent themes emerged from these 34 studies. The 10g monofilament remains a useful clinical tool for detecting severe neuropathy and hence identifying patients at increased risk of ulceration and amputation. However, a consensus on the protocol in the use of the monofilament needs to be reached. Further research regarding the effects of environmental conditions on the accuracy of the monofilament is also essential.

References

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Citations

Apr 16, 2011·Current Diabetes Reports·Vasiliki ArgianaNicholas Tentolouris
Jan 26, 2013·British Journal of Anaesthesia·P CuvillonO Langeron
Mar 25, 2014·Acupuncture in Medicine : Journal of the British Medical Acupuncture Society·Adam P GarrowEdward B Jude
May 9, 2012·Diabetes Research and Clinical Practice·Lawrence A LaveryBijan Najafi
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Jan 24, 2015·Prosthetics and Orthotics International·Oscar L Morey-Vargas, Steven A Smith
Jun 23, 2018·International Journal of Dermatology·Ayesha U Khan, Amor Khachemoune
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Dec 22, 2016·Diabetes Care·Rodica Pop-BusuiDan Ziegler
Apr 3, 2018·Diabetic Medicine : a Journal of the British Diabetic Association·O Binns-HallS Tesfaye
Jun 19, 2019·Journal of Foot and Ankle Research·Jean Paul Vwakya WanzouErisa Sabakaki Mwaka
Nov 19, 2020·Pediatric Diabetes·Gulcin AkinciEva L Feldman
May 20, 2021·BMJ Open Diabetes Research & Care·Varo KirthiUazman Alam

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