PMID: 3749797Jun 1, 1986Paper

The clinical value of faecal bile acid determination in patients with chronic diarrhoea of unknown origin

Scandinavian Journal of Gastroenterology
J J Otte, J R Andersen

Abstract

To evaluate the diagnostic value of faecal total bile acid determination in adult patients with chronic diarrhoea, output and concentration of 3 alpha-hydroxy-bile acids were determined in 28 patients. The patients had normal results of primary biochemical, radiologic, and endoscopic examinations. Stools were sampled for 3 days while on a standardized diet. The patients were observed until final diagnosis was obtained; Crohn's disease was diagnosed in 5 cases, osmotic diarrhoea in 4, bacterial overgrowth in 3, laxative abuse in 2, other specific causes in 3, and persisting lack of specific diagnosis in 11. No difference in output or concentration of faecal bile acids was found between the groups. Six patients with high bile acid outputs benefited from treatment with cholestyramine. Accordingly, determination of total bile acids in stools cannot be recommended as a primary test in patients with chronic diarrhoea.

References

Jul 1, 1979·Digestive Diseases and Sciences·H S MekhjianA F Hofmann
May 1, 1985·Scandinavian Journal of Gastroenterology·E H Thaysen
Jun 1, 1981·The American Journal of Clinical Nutrition·E W BellH H Sandstead

❮ Previous
Next ❯

Citations

Nov 9, 2010·Inflammatory Bowel Diseases·Martin LenicekLibor Vitek
Feb 15, 2007·Current Treatment Options in Gastroenterology·Henrik Westergaard
Jan 1, 1992·Scandinavian Journal of Gastroenterology. Supplement·A J van TilburgM van Blankenstein
Aug 24, 2013·The Journal of Pediatrics·Folke FreudenbergSibylle Koletzko
Oct 1, 1989·American Journal of Reproductive Immunology : AJRI·S GotoS Takeuchi
Jun 3, 2015·Clinical Medicine : Journal of the Royal College of Physicians of London·Oluwafikunayo OrekoyaPeter Paine
Jun 1, 1996·Australian and New Zealand Journal of Medicine·M E CrampD A Cooper
Jul 7, 2012·Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society·D J GracieA C Ford
Jan 27, 2017·BMJ Open Gastroenterology·Ayman BannagaRamesh P Arasaradnam
Jun 20, 2020·The American Journal of Gastroenterology·Michael Camilleri, Priya Vijayvargiya
Sep 1, 2020·Journal of Crohn's & Colitis·Michael Camilleri

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.