The clinical value of hybrid sentinel lymphoscintigraphy to predict metastatic sentinel lymph nodes in breast cancer

Nuclear Medicine and Molecular Imaging
Chang Ju NaSeok Tae Lim

Abstract

Hybrid imaging techniques can provide functional and anatomical information about sentinel lymph nodes in breast cancer. Our aim in this study was to evaluate which imaging parameters on hybrid sentinel lymphoscintigraphy predicted metastatic involvement of sentinel lymph nodes (SLNs) in patients with breast cancer. Among 56 patients who underwent conventional sentinel lymphoscintigraphy, 45 patients (age, 53.1 ± 9.5 years) underwent hybrid sentinel lymphoscintigraphy using a single-photon emission computed tomography (SPECT)/computed tomography (CT) gamma camera. On hybrid SPECT/CT images, we compared the shape and size (long-to-short axis [L/S] ratio) of the SLN, and SLN/periareolar injection site (S/P) count ratio between metastatic and non-metastatic SLNs. Metastatic involvement of sentinel lymph nodes was confirmed by pathological biopsy. Pathological biopsy revealed that 21 patients (46.7 %) had metastatic SLNs, while 24 (53.3 %) had non-metastatic SLNs. In the 21 patients with metastatic SLNs, the SLN was mostly round (57.1 %) or had an eccentric cortical rim (38.1 %). Of 24 patients with non-metastatic SLNs, 13 patients (54.1 %) had an SLN with a C-shape rim or eccentric cortex. L/S ratio was 2.04 for metastatic SLNs an...Continue Reading

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Citations

Jun 2, 2015·Journal of Korean Medical Science·Eun-Mi KimHwan-Jeong Jeong
Apr 27, 2019·Medical & Biological Engineering & Computing·John A KennedyZohar Keidar
Aug 4, 2016·Biomedical Papers of the Medical Faculty of the University Palacký, Olomouc, Czechoslovakia·Milan Simanek, Pavel Koranda
Jun 25, 2019·Nuclear Medicine and Molecular Imaging·Won Woo Lee, UNKNOWN K-SPECT Group
Jun 1, 2017·Nuclear Medicine and Molecular Imaging·Ikdong YooYong-An Chung
Mar 1, 2020·Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine·John A KennedyZohar Keidar

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