The clinical value of the patient-reported multiple sclerosis neuropsychological screening questionnaire

Multiple Sclerosis : Clinical and Laboratory Research
Ilse M NautaBrigit A de Jong

Abstract

Cognitive problems are difficult to identify in patients with multiple sclerosis (MS). To investigate the clinical applicability of the patient-reported MS Neuropsychological Screening Questionnaire (MSNQ-P). Cut-off scores were determined to differentiate between cognitively impaired (n = 90), mildly cognitively impaired (n = 115), and cognitively preserved (n = 147) MS patients using receiver operating characteristic analyses. We could not define specific and sensitive cut-off scores. Higher scores (≥27) did indicate cognitive impairment. Among patients with a higher education, lower scores (<12) indicated intact cognition. Certain scores can indicate intact or impaired cognitive function. Still, MSNQ-P scores should be interpreted with caution.

References

Jun 1, 1983·Acta Psychiatrica Scandinavica·A S Zigmond, R P Snaith
Dec 9, 2004·Multiple Sclerosis : Clinical and Laboratory Research·Ralph H B BenedictFrederick Munschauer
Apr 29, 2006·Journal of the Neurological Sciences·Maria Pia AmatoEmilio Portaccio
Feb 14, 2007·Multiple Sclerosis : Clinical and Laboratory Research·B A ParmenterR H B Benedict
Sep 14, 2007·Archives of Clinical Neuropsychology : the Official Journal of the National Academy of Neuropsychologists·Amanda O'BrienJohn DeLuca
Oct 11, 2008·Multiple Sclerosis : Clinical and Laboratory Research·S VanottiUNKNOWN VANEM Workgroup
Dec 23, 2011·Multiple Sclerosis : Clinical and Laboratory Research·D W LangdonR H B Benedict
Jul 19, 2012·Journal of the Neurological Sciences·Judith M SonderBernard M J Uitdehaag

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Citations

Nov 27, 2019·Clinical Rehabilitation·Nadina B LincolnUNKNOWN CRAMMS Trial Collaborative Group
Apr 27, 2020·Journal of the Neurological Sciences·Zeinab FalsafiMohammad Hossein Harirchian

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