The clinical value of xSPECT/CT Bone versus SPECT/CT. A prospective comparison of 200 scans

European Journal of Hybrid Imaging
Iain Duncan, Nicholas Ingold

Abstract

To prospectively evaluate the clinical utility of xSPECT/CT Bone, a new reconstruction algorithm for single photon emission tomography (SPECT), and compare it with standard SPECT/CT reconstruction. Sequential reporting of SPECT/CT followed by xSPECT/CT images in 200 sequential cases commencing August 2015. Differences between the initial SPECT/CT and the final report (after xSPECT/CT reconstruction) were documented and analysed. 12-18 months after the initial study follow-up, clinical data was sought from a subset of cases in which xSPECT/CT changed the primary diagnosis and imaging correlation undertaken in all patients who subsequently had MRI or CT scans of the same region. A majority of the 200 cases were related to assessment of musculoskeletal complaints. The final (scan) diagnosis was changed after reviewing the xSPECT/CT images in 40 (20%) of cases. The reporting physician (Iain Duncan) assessed that the xSPECT/CT had provided more diagnostic information in 71% of cases. A total of 470 additional lesions were found, equivalent to 2.4 lesions per case. In 33 cases of imaging follow-up there was a high degree of correlation with bone scan findings and xSPECT correlated better than SPECT in regard to detailed findings. In ...Continue Reading

References

Jun 23, 2004·Nuclear Medicine Communications·Orazio SchillaciGiovanni Simonetti
Mar 24, 2006·Academic Radiology·Wolfgang RömerTorsten Kuwert
Feb 13, 2009·Joint, Bone, Spine : Revue Du Rhumatisme·Philippe GoupilleDaniel Wendling
Aug 4, 2009·Seminars in Nuclear Medicine·Dominique DelbekeRichard L Wahl
Dec 18, 2009·European Journal of Nuclear Medicine and Molecular Imaging·Vincent HelyarIgnac Fogelman
Aug 16, 2017·BioMed Research International·Olivier RagerOsman Ratib

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Citations

Jul 1, 2020·EJNMMI Research·Noriaki MiyajiMasahisa Onoguchi
Jul 1, 2021·European Journal of Hybrid Imaging·Thiago V M LimaKlaus Strobel
Aug 12, 2021·Nuklearmedizin. Nuclear Medicine·Michael Thomas BeckTilo Schlittenbauer

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