The clustering of psychopathology among adults seeking treatment for alcohol and drug addiction

Journal of Substance Abuse Treatment
Karen UrbanoskiBrian Rush

Abstract

Beyond the high prevalence of co-occurring mental and substance use disorders, little is known about more complex patterns of psychopathology and multimorbidity, particularly in treatment populations. We sought to identify a parsimonious set of latent classes to describe the structure of mental disorder comorbidity among adults entering outpatient addiction treatment, and explore differences in the structure and prevalence of classes across sociodemographic characteristics. Participants (N=544) completed the Psychiatric Diagnostic Screening Questionnaire at treatment admission. We used latent class analysis to identify classes of clients with specific patterns of co-occurring mental disorders. The best-fitting solution identified 3 classes, characterized by no comorbidity (i.e., substance use disorders only), co-occurring major depression, and multimorbidity or a high degree of psychopathology. Older age was associated with lower probability of being in the class with co-occurring major depression, women were more likely than men to be in the multimorbid class, and being married or partnered was associated with a lower probability of being in either of the comorbid classes. These results are consistent with general population r...Continue Reading

References

Feb 7, 2001·The British Journal of Psychiatry : the Journal of Mental Science·G AndrewsW Hall
May 12, 2001·Comprehensive Psychiatry·Mark Zimmerman, J I Mattia
Sep 6, 2001·Archives of General Psychiatry·Mark Zimmerman, J I Mattia
May 3, 2003·The American Journal of Psychiatry·Wilson M ComptonEdward L Spitznagel
Dec 30, 2004·Social Psychiatry and Psychiatric Epidemiology·Sami P PirkolaJouko K Lönnqvist
Jun 9, 2005·Archives of General Psychiatry·Ronald C KesslerEllen E Walters
Feb 16, 2006·The Australian and New Zealand Journal of Psychiatry·Simon J AdamsonJoel Porter
Apr 21, 2007·Journal of Studies on Alcohol and Drugs·Douglas L Polcin, Martha Beattie
Jun 19, 2007·Journal of Substance Abuse Treatment·Patrick M Flynn, Barry S Brown
Aug 25, 2007·Annual Review of Clinical Psychology·Robert F Krueger, Kristian E Markon
Oct 10, 2007·The Australian and New Zealand Journal of Psychiatry·Kathryn D BakerAlison R Yung
Nov 30, 2010·Comprehensive Psychiatry·Uma VaidyanathanWilliam G Iacono
Jul 16, 2011·Comprehensive Psychiatry·Thomas M OlinoPeter M Lewinsohn
Nov 2, 2011·European Addiction Research·Anne-Marit LangåsStein Opjordsmoen
Aug 28, 2013·Journal of Psychiatric Research·Renée El-GabalawyRobert H Pietrzak
Jan 30, 2014·Journal of Clinical Epidemiology·W Scott Richardson, Lynn M Doster
Jan 30, 2014·Journal of Clinical Epidemiology·Alexandra Prados-TorresMarjan van den Akker
Mar 7, 2014·Drug and Alcohol Dependence·Jessica L LarsenMerith Cosden

Citations

Apr 1, 2015·Journal of Medicinal Chemistry·Thomas M KeckAmy Hauck Newman
May 21, 2015·Community Mental Health Journal·Emily M MayLeonard A Jason
Aug 6, 2016·Journal of Dual Diagnosis·Rodrigo Marín-NavarreteJosé Fernández-Mondragón
Jul 20, 2016·Journal of Addictive Diseases·Kate Wolitzky-TaylorAdam M Leventhal
Oct 26, 2016·Journal of Substance Abuse Treatment·Christophe HuỳnhMarie-Josée Fleury
Jan 12, 2017·Revista brasileira de psiquiatria : orgão oficial da Associação Brasileira de Psiquiatria, Asociación Psiquiátrica de la América Latina·Luis Villalobos-GallegosHugo González-Cantú
Jun 21, 2019·The Psychiatric Quarterly·Marie-Josée FleuryJean-Marie Bamvita
Feb 28, 2021·Psychiatry Research·Taylor BrownKaterina Matsa

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Spatio-Temporal Regulation of DNA Repair

DNA repair is a complex process regulated by several different classes of enzymes, including ligases, endonucleases, and polymerases. This feed focuses on the spatial and temporal regulation that accompanies DNA damage signaling and repair enzymes and processes.

Glut1 Deficiency

Glut1 deficiency, an autosomal dominant, genetic metabolic disorder associated with a deficiency of GLUT1, the protein that transports glucose across the blood brain barrier, is characterized by mental and motor developmental delays and infantile seizures. Follow the latest research on Glut1 deficiency with this feed.

Hereditary Sensory Autonomic Neuropathy

Hereditary Sensory Autonomic Neuropathies are a group of inherited neurodegenerative disorders characterized clinically by loss of sensation and autonomic dysfunction. Here is the latest research on these neuropathies.

Separation Anxiety

Separation anxiety is a type of anxiety disorder that involves excessive distress and anxiety with separation. This may include separation from places or people to which they have a strong emotional connection with. It often affects children more than adults. Here is the latest research on separation anxiety.

Neural Activity: Imaging

Imaging of neural activity in vivo has developed rapidly recently with the advancement of fluorescence microscopy, including new applications using miniaturized microscopes (miniscopes). This feed follows the progress in this growing field.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Related Papers

Psychiatric Services : a Journal of the American Psychiatric Association
Haiyi XieRobert E Drake
Journal of Clinical Psychopharmacology
Ismene L PetrakisVA VISN I MIRECC Study Group
© 2021 Meta ULC. All rights reserved