PMID: 15376668Sep 21, 2004Paper

The cochlear amplifier as a standing wave: "squirting" waves between rows of outer hair cells?

The Journal of the Acoustical Society of America
Andrew Bell, Neville H Fletcher

Abstract

This paper draws attention to symmetric Lloyd-Redwood (SLR) waves-known in ultrasonics as "squirting" waves-and points out that their distinctive properties make them well-suited for carrying positive feedback between rows of outer hair cells. This could result in standing-wave resonance-in essence a narrow-band cochlear amplifier. Based on known physical properties of the cochlea, such an amplifier can be readily tuned to match the full 10-octave range of human hearing. SLR waves propagate in a thin liquid layer enclosed between two thin compliant plates or a single such plate and a rigid wall, conditions found in the subtectorial space of the cochlea, and rely on the mass of the inter-plate fluid interacting with the stiffness of the plates to provide low phase velocity and high dispersion. The first property means SLR wavelengths can be as short as the distance between rows of outer hair cells, allowing standing wave formation; the second permits wide-range tuning using only an order-of-magnitude variation in cochlear physical properties, most importantly the inter-row spacing. Viscous drag at the two surfaces potentially limits SLR wave propagation at low frequencies, but this can perhaps be overcome by invoking hydrophobic...Continue Reading

References

Aug 1, 1967·The Annals of Otology, Rhinology, and Laryngology·M Schiff, H Christiensen-Lou
Jan 1, 1983·Hearing Research·H Davis
Sep 15, 1993·Proceedings of the National Academy of Sciences of the United States of America·B N Evans, P Dallos
Nov 21, 1998·Hearing Research·R C Naidu, D C Mountain
Mar 31, 1999·Proceedings of the National Academy of Sciences of the United States of America·H LöwenheimH P Zenner
Mar 29, 2000·Proceedings of the National Academy of Sciences of the United States of America·S CamaletJ Prost
Aug 11, 2001·Physical Review Letters·V S CraigD R Williams
Sep 5, 2001·Physical Review Letters·Y Zhu, S Granick
Apr 12, 2003·Nature Materials·Steve GranickHyunjung Lee
Apr 12, 2003·Nature Materials·Cécile Cottin-BizonneElisabeth Charlaix
May 7, 2003·Physical Review Letters·Thomas Duke, Frank Jülicher
Jun 24, 2003·Nature Materials·Aurélie Lafuma, David Quéré
Aug 29, 2003·The Journal of the Acoustical Society of America·Eric L LePage
Feb 6, 2007·Biophysical Journal·K Domenica Karavitaki, David C Mountain

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Citations

Oct 6, 2005·Biological cybernetics·Katarzyna J BlinowskaWieslaw Konopka
Jan 12, 2007·Biological cybernetics·Andrew Bell
Jun 7, 2005·Hearing Research·Robert H WithnellAngela Thomsen
Oct 16, 2004·PLoS Biology·Andrew Bell
Jun 2, 2012·PloS One·Katarzyna J BlinowskaHenryk Skarzynski
Nov 13, 2012·PloS One·Andrew Bell
Apr 29, 2006·The Journal of the Acoustical Society of America·W Wiktor JedrzejczakWieslaw Konopka
Dec 21, 2010·Journal of Basic and Clinical Physiology and Pharmacology·Cahtia AdelmanHaim Sohmer
Oct 2, 2007·Physiological Measurement·Katarzyna J BlinowskaWieslaw Konopka
Jun 18, 2017·Scientific Reports·Nikola CiganovićTobias Reichenbach

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