The coding of head orientations in neurons of bilateral vestibular nuclei of cats after unilateral labyrinthectomy: response to off-vertical axis rotation

Experimental Brain Research
Y S Chan

Abstract

In decerebrate cats that had been acutely hemilabyrinthectomized (HL), the extracellular activities of vestibular nuclear neurons on the lesioned and labyrinth-intact sides were studied during constant-velocity off-vertical axis rotations (OVAR) in the clockwise (CW) and counterclockwise (CCW) directions (at 10 degrees tilt). Over the range of 1.75-15 degrees/s, two types of neuronal responses were identified on both sides. Some neurons showed symmetric and velocity-stable bidirectional response sensitivity (delta defined as the CW gain over the CCW gain) while other neurons exhibited asymmetric and velocity-variable delta. The mathematically derived gain tuning ratios of these two groups of neurons were within the range of one-dimensional and two-dimensional neurons respectively. The best response orientations in one-dimensional neurons and the orientations of the maximum response vector, S(max), in two-dimensional neurons were found to point in all directions on the horizontal plane. On the labyrinth-intact side, both the one-dimensional and two-dimensional neurons showed asymmetry in the neuron numbers and/or the response gains between the two roll quadrants as well as between the two pitch quadrants. In addition, both the n...Continue Reading

Citations

May 10, 2006·Experimental Brain Research·Ying-Shing ChanDaisy Kwok-Yan Shum
Feb 3, 2004·The Journal of Comparative Neurology·Chun-Hong LaiYing-Shing Chan
May 11, 2000·Journal of Neurophysiology·D E AngelakiJ D Dickman

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