The Collaborative Hospital Transfusion Study: variations in use of autologous blood account for hospital differences in red cell use during primary hip and knee surgery

Transfusion
W H ChurchillD M Surgenor

Abstract

Red cell use in patients undergoing Diagnosis Related Group (DRG) 209 procedures (major joint and limb reconstruction procedures of the lower extremities) has been shown to have large, unexplained interhospital variations. Abstracted records of 2590 consecutive DRG 209 patients at five university hospitals from January 1992 to December 1993 were stratified by procedure and preoperative blood deposit status. Patient characteristics and transfusion and in-hospital outcomes were compared across hospitals. Blood use among patients who did not preoperatively deposit blood was similar across hospitals. Significant differences were found across hospitals for total hip replacement patients in the percentage of patients preoperatively depositing blood (59-80%), percentage of patients receiving transfusion(s) (51 to > 99%), the mean number of units collected per patient (1.6-2.9), and the mean number of unused autologous units per 100 patients (1-185). No significant differences were found in the percentage of those who deposited blood and then required allogeneic units. There was little variability in length of hospital stay or in last hematocrits. Findings were similar for total knee replacement patients. Interhospital variations in re...Continue Reading

Citations

Nov 11, 2010·Archives of Orthopaedic and Trauma Surgery·Devendra MahadevanJonathan Keenan
Apr 23, 2002·Transfusion Medicine·K TitlestadJ Georgsen
Mar 16, 2002·Transfusion·Sean M BerenholtzMichael J Klag
Feb 11, 1999·The New England Journal of Medicine·L T GoodnoughJ P AuBuchon
Jul 18, 2012·Annals of Surgery·Feng QianLaurent G Glance
Dec 24, 2005·Biomedizinische Technik. Biomedical Engineering·M WojanA Wild
Feb 22, 2012·Blood Coagulation & Fibrinolysis : an International Journal in Haemostasis and Thrombosis·Angela NotarnicolaBiagio Moretti
Jan 13, 2012·Transfusion Medicine Reviews·Torunn Oveland ApelsethNancy M Heddle
Aug 13, 2015·Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract·Christopher T AquinaFergal J Fleming
Apr 17, 2016·Journal of Oral and Maxillofacial Surgery : Official Journal of the American Association of Oral and Maxillofacial Surgeons·Jesper Jared OlsenJohannes Jakobsen Sidelmann
Mar 31, 2004·The American Journal of Medicine·Aryeh ShanderRichard Spence
Jun 22, 2016·The Journal of Arthroplasty·Mariano E MenendezBrian T Bateman
Nov 8, 2002·Transfusion·Susan D RoseffCatherine S Manno
Aug 23, 2002·Acta Anaesthesiologica Scandinavica·H GehringP Schmucker
Apr 16, 2003·British Journal of Haematology·A J G JansenD J Van Rhenen
Oct 4, 2013·The Journal of Bone and Joint Surgery. American Volume·Jai Hyung ParkJavad Parvizi
Feb 11, 2003·The Medical Clinics of North America·Barbara Armas-LoughranJeffrey L Carson

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