The colocalization of substance P- and somatostatin-like peptides in neurons of the entopeduncular nucleus of rats.

Peptides
S MurakamiH Takagi

Abstract

The colocalization of substance P-like and somatostatin-like immunoreactivity in cell bodies was investigated in the entopeduncular nucleus of rats by a double immunofluorescence method using species specific antibodies. Most of the substance P-like immunoreactive cells were also positive to somatostatin and mainly seen in the rostral to middle region of the entopeduncular nucleus. Therefore it is suggested that double-labeled neurons in the entopeduncular nucleus project to the lateral habenular nucleus which is involved in the limbic system, since the rostral portion of the entopeduncular nucleus has been shown to project to the lateral habenular nucleus.

References

Mar 1, 1978·The Journal of Comparative Neurology·A C Cuello, I Kanazawa
Oct 1, 1976·The Journal of Comparative Neurology·R KimM B Carpenter
Aug 8, 1985·The Journal of Comparative Neurology·S R VincentJ C Brown
Nov 8, 1958·Nature·C C CURTAIN

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