The combined application of magnetic resonance DTI and 3D-pcASL in differential diagnosis of hyper-acute and acute ischemic cerebral infarction

Zhonghua yi xue za zhi
Z Y DaiZ P Zhang

Abstract

Objective: To explore the clinical value of magnetic resonance diffusion tensor imaging (DTI) combined with 3D pseudo continuous arterial spin labeling (3D-pcASL) perfusion imaging in differential diagnosis of hyper-acute and acute ischemic cerebral infarction. Methods: A total of 42 patients with confirmed unilateral ischemic cerebral infarction from February 2015 to October 2017 of Affiliated Yancheng Hospital of Southeast University Medical College were collected. DTI and 3D-pcASL images of hyper-acute (14 patients, group A) and acute (28 patients, group B) ischemic cerebral infarction were retrospectively analyzed. The slice with the biggest lesion on diffusion weighted imaging (DWI) was selected to measure the infarction area (S(DWI)) and abnormal cerebral blood flow (CBF) perfusion area (S(CBF)). Regions of interest (ROIs) were set on the infarction core (IC) area, mismatch area of S(CBF) and S(DWI) (MACD), and their corresponding contralateral regions. The values of CBF, average diffusion coefficient (DC(avg)), and fractional anisotropy (FA) parameter images in these ROIs in patients with both S(CBF)>S(DWI) and lower perfusion in the IC were recorded. The relative values of each infarction lesion to its corresponding con...Continue Reading

Related Concepts

Related Feeds

Attention Disorders

Attention is involved in all cognitive activities, and attention disorders are reported in patients with various neurological diseases. Here are the latest discoveries pertaining to attention disorders.