Jan 1, 1977

The combined influence of the stimulus frequency of the vagal nerves and the atrial stimulus interval on the atrioventricular conduction time

Cardiovascular Research
E L de BeerB Naafs


The way in which the A-V node adapts its conduction time to stepwise alterations of atrial stimulation rates was studied under different conditions of vagal nerve activity (open chest, anaesthetised rabbit). Increase of stimulation rate induced oscillatory adaptation to a longer conduction time. Decrease caused shorter conduction times without oscillation. The time constant did not differ. Oscillation amplitude and time constants were markedly influenced by vagal activity. The observed phenomena can be explained on the basis of a time and voltage dependent K+ conductance.

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Mentioned in this Paper

Vagus Nerve Structure
Anterior Thoracic Region
Chinchilla Rabbits
Atrial Function
Cardiac Conduction System
Structure of Atrioventricular Node

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