The common neural bases between sexual desire and love: a multilevel kernel density fMRI analysis

The Journal of Sexual Medicine
Stephanie CacioppoJames W Lewis

Abstract

One of the most difficult dilemmas in relationship science and couple therapy concerns the interaction between sexual desire and love. As two mental states of intense longing for union with others, sexual desire and love are, in fact, often difficult to disentangle from one another. The present review aims to help understand the differences and similarities between these two mental states using a comprehensive statistical meta-analyses of all functional magnetic resonance imaging (fMRI) studies on sexual desire and love. Systematic retrospective review of pertinent neuroimaging literature. Review of published literature on fMRI studies illustrating brain regions associated with love and sexual desire to date. Sexual desire and love not only show differences but also recruit a striking common set of brain areas that mediate somatosensory integration, reward expectation, and social cognition. More precisely, a significant posterior-to-anterior insular pattern appears to track sexual desire and love progressively. This specific pattern of activation suggests that love builds upon a neural circuit for emotions and pleasure, adding regions associated with reward expectancy, habit formation, and feature detection. In particular, the ...Continue Reading

References

Jan 30, 1999·Psychoneuroendocrinology·B R Komisaruk, B Whipple
Dec 23, 1999·Current Opinion in Neurobiology·J G Pfaus
Dec 16, 2000·Neuroreport·A Bartels, S Zeki
Mar 1, 2002·Human Brain Mapping·Sherif KaramaMario Beauregard
May 16, 2002·BJOG : an International Journal of Obstetrics and Gynaecology·Rosemary Basson
Oct 17, 2003·Psychiatry Research·Serge StoléruJean François Pujol
Jun 2, 2005·Journal of Neurophysiology·Arthur AronLucy L Brown
Jul 26, 2005·Biological Psychology·Rudolf StarkDieter Vaitl
Feb 10, 2006·International Journal of Impotence Research·S W KimJ-H Chae
May 11, 2006·The Neuroscientist : a Review Journal Bringing Neurobiology, Neurology and Psychiatry·James W Lewis
Sep 19, 2006·NeuroImage·Jorge PonsetiHartwig R Siebner
Jul 3, 2007·NeuroImage·Stephanie OrtigueFrancesco Bianchi-Demicheli
Jul 18, 2008·Social Neuroscience·Francesco Bianchi-DemicheliStephanie Ortigue
Jul 24, 2008·Behavioral and Brain Functions : BBF·Mira BühlerMichael N Smolka
Aug 30, 2008·Medical Hypotheses·Stephanie Ortigue, Francesco Bianchi-Demicheli
Aug 30, 2008·PloS One·Hideaki Kawabata, Semir Zeki
Sep 2, 2008·NeuroImage·Stephanie Ortigue, Francesco Bianchi-Demicheli
Dec 10, 2008·NeuroImage·Tor D WagerJared X Van Snellenberg
Mar 27, 2009·Psychiatry Research·Mario BeauregardEvelyne Landry St-Pierre
May 21, 2009·The Journal of Sexual Medicine·James G Pfaus
May 21, 2009·The Journal of Sexual Medicine·Stephanie OrtigueFrancesco Bianchi-Demicheli
Sep 3, 2010·The Journal of Sexual Medicine·Stephanie OrtigueJames W Lewis
May 24, 2011·The Journal of Sexual Medicine·Simone Kühn, Jürgen Gallinat
Jul 2, 2011·The Journal of Sexual Medicine·Francesco Bianchi-DemicheliStephanie Ortigue
Sep 3, 2011·The Journal of Sexual Medicine·Sabine KagererRudolf Stark

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Citations

Dec 1, 2012·CNS Spectrums·Donatella MarazzitiUbaldo Bonuccelli
Oct 1, 2013·Social Cognitive and Affective Neuroscience·Sarita SilveiraKristina Hennig-Fast
Jul 9, 2013·Progrès en urologie : journal de l'Association française d'urologie et de la Société française d'urologie·F CourF Giuliano
Sep 5, 2013·Scientific Reports·Stephanie CacioppoJohn T Cacioppo
Jun 4, 2014·World Psychiatry : Official Journal of the World Psychiatric Association (WPA)·John T CacioppoAbraham A Palmer
Apr 12, 2016·Frontiers in Behavioral Neuroscience·Yiwen WangStephanie Cacioppo
Oct 4, 2014·Parkinsonism & Related Disorders·Michele PolettiUbaldo Bonuccelli
Feb 5, 2013·Current Opinion in Neurobiology·Kent C Berridge, Morten L Kringelbach
May 8, 2015·Neuron·Kent C Berridge, Morten L Kringelbach
Mar 19, 2014·Biological Psychology·Junqiang DaiYue-jia Luo
Jan 18, 2015·The Journal of Adolescent Health : Official Publication of the Society for Adolescent Medicine·Devon J HenselJ Dennis Fortenberry
Mar 13, 2015·Frontiers in Human Neuroscience·Hongwen SongXiaochu Zhang
Mar 29, 2014·Frontiers in Human Neuroscience·Serge Stoléru
Nov 8, 2016·Social Neuroscience·Nichol M L WongTatia M C Lee
Apr 21, 2016·PloS One·Franziska EmmerlingAlexander Thomas Sack
Mar 28, 2017·Perspectives on Psychological Science : a Journal of the Association for Psychological Science·Terri ConleyAli Ziegler
Jul 18, 2014·Psychological Science·Mylene BolmontStephanie Cacioppo
Oct 20, 2017·Social Neuroscience·Stephanie CacioppoGeorge Monteleone
Jun 14, 2018·Social Cognitive and Affective Neuroscience·Lisa J M van den BergBernet M Elzinga
Jan 15, 2016·Sexually Transmitted Diseases·Fei HeJ Dennis Fortenberry
Jan 10, 2020·Journal of Sex & Marital Therapy·Laura M Vowels, Kristen P Mark
Sep 12, 2017·Frontiers in Behavioral Neuroscience·Stephanie CacioppoGeorge Monteleone
Jul 22, 2018·Frontiers in Pharmacology·Marco Leonti, Laura Casu
Jun 19, 2018·Frontiers in Psychology·Xiaoping YingJin Fan
Sep 20, 2018·International Journal of Impotence Research·José Nuno Trovão, Ege Can Serefoglu
Apr 30, 2021·Frontiers in Psychology·Adam Bode, Geoff Kushnick
Aug 30, 2021·Biological Psychiatry·Michael A FergusonMichael D Fox

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