The Comparative Harms of Open and Robotic Prostatectomy in Population Based Samples.

The Journal of Urology
Brock O'NeilDavid F Penson

Abstract

Robotic assisted radical prostatectomy has largely replaced open radical prostatectomy for the surgical management of prostate cancer despite conflicting evidence of superiority with respect to disease control or functional sequelae. Using population cohort data, in this study we examined sexual and urinary function in men undergoing open radical prostatectomy vs those undergoing robotic assisted radical prostatectomy. Subjects surgically treated for prostate cancer were selected from 2 large population based prospective cohort studies, the Prostate Cancer Outcomes Study (enrolled 1994 to 1995) and the Comparative Effectiveness Analysis of Surgery and Radiation (enrolled 2011 to 2012). Subjects completed baseline, 6-month and 12-month standardized patient reported outcome measures. Main outcomes were between-group differences in functional outcome scores at 6 and 12 months using linear regression, and adjusting for baseline function, sociodemographic and clinical characteristics. Sensitivity analyses were used to evaluate outcomes between patients undergoing open radical prostatectomy and robotic assisted radical prostatectomy within and across CEASAR and PCOS. The combined cohort consisted of 2,438 men, 1,505 of whom underwent...Continue Reading

References

Nov 14, 2006·European Urology·Mani MenonJames O Peabody
May 12, 2009·BJU International·Bernardo RoccoOttavio de Cobelli
Jul 22, 2009·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Ronald C ChenJames A Talcott
Oct 15, 2009·JAMA : the Journal of the American Medical Association·Jim C HuNancy L Keating
May 29, 2012·BMC Cancer·Robert A GardinerSuzanne Kathleen Chambers
Oct 17, 2012·The Journal of Urology·Christopher B AndersonDaniel A Barocas
May 15, 2013·European Urology·Quoc-Dien TrinhAndrew J Vickers
Nov 19, 2013·Journal of Comparative Effectiveness Research·Daniel A BarocasDavid F Penson
Apr 16, 2014·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Giorgio GandagliaQuoc-Dien Trinh
Oct 14, 2014·European Urology·Anna WallerstedtUNKNOWN LAPPRO steering committee
Dec 23, 2014·Urology·Ted A SkolarusUNKNOWN PROSTQA Consortium

❮ Previous
Next ❯

Citations

Apr 18, 2016·The Journal of Urology·Michael O Koch
Sep 17, 2016·Expert Review of Anticancer Therapy·Paolo CapogrossoXavier Cathelineau
Apr 21, 2017·Current Opinion in Urology·Jathin BandariBruce L Jacobs
Oct 2, 2017·Current Urology Reports·Fabio CastiglioneAsif Muneer
Jul 25, 2018·Minerva chirurgica·Clément C Abbou, Ahmed Abdelbary
Jul 25, 2018·Minerva chirurgica·Matteo ManfrediFrancesco Porpiglia
Aug 31, 2016·The World Journal of Men's Health·Paolo CapogrossoFrancesco Montorsi
Jul 11, 2020·International Braz J Urol : Official Journal of the Brazilian Society of Urology·Yingyi QinJia He
Dec 20, 2016·The Journal of Urology·Christian Stief, Martin Gleave
Jul 21, 2017·International Braz J Urol : Official Journal of the Brazilian Society of Urology·Lucas Medeiros BurttetBrasil Silva
Feb 12, 2021·Asian Journal of Urology·Marcio Covas MoschovasVipul R Patel
Jul 1, 2021·Patient Preference and Adherence·Graham R HaleRyan W Dobbs

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.