The complement system in chronic lymphocytic leukemia: a possible role in autoimmune manifestations

Leukemia & Lymphoma
G Lugassy, M Schlesinger

Abstract

We describe the complement system of three CLL patients who developed autoimmune complications in the course of their disease. The complement profile was pathological in both CLL patients with active autoimmune diseases, while it showed no deficiency in the patient with quiescent autoimmunity. The complement profile could be an early marker for development of autoimmunity in CLL patients

References

Oct 1, 1990·Annals of Internal Medicine·K A FoonR P Gale
Jan 1, 1989·The Journal of Experimental Medicine·Z M SthoegerN Chiorazzi
Mar 1, 1989·Calcified Tissue International·Y DoiH Shimokawa
Oct 1, 1987·Journal of Clinical Pharmacology·M A WeberR C Klein
Jul 1, 1986·Journal of Clinical Pathology·T J HamblinB J Young
May 1, 1985·American Journal of Hematology·M E Heath, B D Cheson
Sep 1, 1965·Immunochemistry·G ManciniJ F Heremans
Dec 1, 1969·Arthritis and Rheumatism·G J GoldenbergL G Israels

❮ Previous
Next ❯

Related Concepts

Related Feeds

CNS Lymphoma

In CNS lymphoma, cancerous cells from lymph tissues or other parts of the body form tumors in the brain and/or spinal cord. Here is the latest research on this rare non-Hodgkin lymphoma.

Autoimmune Diseases

Autoimmune diseases occur as a result of an attack by the immune system on the body’s own tissues resulting in damage and dysfunction. There are different types of autoimmune diseases, in which there is a complex and unknown interaction between genetics and the environment. Discover the latest research on autoimmune diseases here.

B-Cell Leukemia (Keystone)

B-cell leukemia includes various types of lymphoid leukemia that affect B cells. Here is the latest research on B-cell leukemia.