The complete genome analysis of Crimean-Congo hemorrhagic fever virus isolated in Turkey

Virus Research
Aykut OzdarendeliA Kalkan

Abstract

Crimean-Congo hemorrhagic fever virus (CCHFV) is the causative agent of a tick-borne disease with high mortality rates in humans. The distribution of CCHFV includes over 30 countries in Asia, the Middle East, southeastern Europe, and Africa. It was first recognized in Turkey in 2002, with an increasing number of cases reported between 2002 and 2009. Recent analysis of complete genome sequences of CCHFV isolates has revealed that the genomic plasticity of the virus is surprisingly high for an arthropod-borne virus. We have determined the complete nucleotide and deduced amino acid sequences of strain CCHFV Turkey-Kelkit06 isolated from the blood of a patient in an endemic region of Turkey in 2006. The complete sequence length of the CCHFV Turkey-Kelkit06 strain is 19,186 nt, consisting of a 1673 nt S segment, a 5364 nt M segment, and a 12,149 nt L segment. Based on the analysis of S, M, and L segments, CCHFV Turkey-Kelkit06 clustered in Group V, which represents the Europe/Turkey geographic lineage. Although glycoproteins encoded by the M gene are the most variable part of the CCHFV Turkey-Kelkit06 strain, some functional domains of the glycoproteins are well conserved. Here, we report the complete sequence and genome organizatio...Continue Reading

References

Aug 1, 1996·The Journal of General Virology·A C Marriott, P A Nuttall
Sep 1, 1997·Nucleic Acids Research·S F AltschulD J Lipman
Jun 20, 2002·Journal of Virology·Angela J SanchezStuart T Nichol
Apr 15, 2003·The Journal of General Virology·Lyudmila YashinaVladimir Petrov
Mar 23, 2004·Virology·Jessica E HonigStuart T Nichol
Jun 25, 2004·Nucleic Acids Research·Burkhard RostJinfeng Liu
Sep 28, 2004·The Journal of General Virology·Roger HewsonChristopher Clegg
Oct 22, 2004·Emerging Infectious Diseases·S Sami KartiThomas G Ksiazek
Jul 22, 2005·The Journal of General Virology·Alexander N Lukashev
Mar 24, 2006·The Lancet Infectious Diseases·Onder Ergönül
Aug 17, 2006·Journal of Virology·Varough M DeydeStuart T Nichol
Nov 8, 2006·Journal of Clinical Microbiology·Sukru TonbakAykut Ozdarendeli
Apr 21, 2007·Nature Protocols·Olof EmanuelssonHenrik Nielsen
May 10, 2007·Molecular Biology and Evolution·Koichiro TamuraSudhir Kumar
Jun 8, 2007·BMC Infectious Diseases·Kenan MidilliFrans Jongejan
Jun 30, 2009·Infection, Genetics and Evolution : Journal of Molecular Epidemiology and Evolutionary Genetics in Infectious Diseases·Vassiliki Anagnostou, Anna Papa

❮ Previous
Next ❯

Citations

Mar 28, 2012·Vector Borne and Zoonotic Diseases·Agustín Estrada-PeñaAdrián Estrada-Sánchez
Dec 24, 2015·Antiviral Research·Hakan LeblebiciogluIrfan Sencan
Aug 22, 2012·Journal of Virological Methods·Engin BerberAykut Ozdarendeli
Sep 12, 2018·Acta Microbiologica Et Immunologica Hungarica·Umut Safiye Say Coskun, Zahide Asık
Sep 20, 2020·Antiviral Research·Koray ErgünayAykut Özkul
Sep 7, 2020·Travel Medicine and Infectious Disease·Enrica SerretielloMassimiliano Galdiero
Sep 5, 2021·International Journal of Clinical Practice·Sawai Singh RathoreDeep Manojkumar Patel
Dec 2, 2021·PLoS Neglected Tropical Diseases·Elif KaraaslanMehmet Ziya Doymaz
Dec 18, 2012·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·C FilipponeN Tordo

❮ Previous
Next ❯

Related Concepts

Related Feeds

Argentine Hemorrhagic Fever

Argentine hemorrhagic fever (AHF) is an endemo-epidemic disease caused by junín virus (JUNV), a member of the arenaviridae family. Discover the latest research on AHF here.

Babesiosis

Babesiosis is caused by parasites of the genus babesia, which are transmitted in nature by the bite of an infected tick. Discover the latest research on babesiosis here.