The complete mitochondrial genome of Metorchis orientalis (Trematoda: Opisthorchiidae): Comparison with other closely related species and phylogenetic implications

Infection, Genetics and Evolution : Journal of Molecular Epidemiology and Evolutionary Genetics in Infectious Diseases
Lu NaChun-Ren Wang

Abstract

Metorchis orientalis (Trematoda: Opisthorchiidae) is an important trematode infecting many animals and humans, causing metorchiasis. In the present study, the complete mitochondrial (mt) genome of M. orientalis was sequenced. The complete mt genome of M. orientalis is 13,834 bp circular DNA molecule and contains 12 protein-coding genes, 22 transfer RNA genes, and two ribosomal RNA genes. The gene content and arrangement of M. orientalis is the same as those of Opisthorchiidae trematodes (Opisthorchis viverrini, Opisthorchis felineus and Clonorchis sinensis), but distinct from Schistosoma spp. Phylogenetic analyses using concatenated amino acid sequences of 12 protein-coding genes with three different computational algorithms (Bayesian inference, maximum likelihood and maximum parsimony) revealed that M. orientalis and O. viverrini represent sister taxa. The mt genome provides a novel genetic marker for further studies of the identification, classification and molecular epidemiology of Opisthorchiidae trematodes, and should have implications for the diagnosis, prevention and control of metorchiasis in animals and humans.

References

Sep 12, 2001·Molecular and Biochemical Parasitology·T H LeD P McManus
May 2, 2002·Trends in Parasitology·Thanh H LeDonald P McManus
Aug 13, 2003·Bioinformatics·Fredrik Ronquist, John P Huelsenbeck
Apr 5, 2007·Nature Protocols·Robin B GasserXingquan Zhu
Nov 13, 2009·Parasitology International·Sergei V ShekhovtsovViatcheslav A Mordvinov
Aug 16, 2011·Parasitology International·Viatcheslav A MordvinovAleksey V Katokhin
Sep 21, 2011·Infection, Genetics and Evolution : Journal of Molecular Epidemiology and Evolutionary Genetics in Infectious Diseases·Yu WangXing-Quan Zhu
Aug 29, 2012·Infection, Genetics and Evolution : Journal of Molecular Epidemiology and Evolutionary Genetics in Infectious Diseases·Guo-Hua LiuXing-Quan Zhu
Jan 19, 2013·Molecular Biology and Evolution·Kazutaka Katoh, Daron M Standley
Feb 12, 2014·The Korean Journal of Parasitology·Dongmin LeeKeeseon S Eom

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Citations

Oct 23, 2016·Infection, Genetics and Evolution : Journal of Molecular Epidemiology and Evolutionary Genetics in Infectious Diseases·Thanh Hoa LeDavid Blair
Mar 9, 2020·The Korean Journal of Parasitology·Rongkun RanGuoqing Li

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