The complexation of metal cations by D-galacturonic acid: a spectroscopic study

Carbohydrate Research
Andriy SynytsyaKarel Volka

Abstract

Solid complexes of D-galacturonic acid (GalA) with cobalt(II), copper(II), nickel(II) and oxovanadium(IV) (1-4) were prepared and characterised. The metal-to-ligand molar ratio was 1:2 for complexes 1-3 and 1:1 for complex 4. The alpha- and beta-anomers of GalA were detected in all the complexes in solid state and in solutions. An addition of small amounts of the paramagnetic complexes to the D2O solution of pure ligand led to NMR line broadening of some 1H and 13C nuclei. This broadening was sensitive to the anomeric state of GalA in the case of complexes 1 and 4. NMR and vibrational spectroscopic data indicate the formation of carboxylate complexes of all the cations, while noncarboxylic oxygens are also involved into the metal bonding in some cases. VCD spectra of complexes 1-4 in D2O and Me2SO-d6 solutions confirm that GalA carboxylic group may participate in the formation of optically active species around the metal cation. Possible ways of GalA coordination by metal cations of this study were proposed and discussed.

References

Feb 1, 1997·Critical Reviews in Food Science and Nutrition·B R ThakurA K Handa
Apr 16, 1999·Chemosphere·M T KartelB K Veisov
Jul 6, 2000·Proceedings of the National Academy of Sciences of the United States of America·R A SilvaT A Keiderling
Dec 13, 2002·Spectrochimica Acta. Part A, Molecular and Biomolecular Spectroscopy·Vladimir SetnickaKarel Volka

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Citations

Jun 9, 2016·Dalton Transactions : an International Journal of Inorganic Chemistry·Manuel I VelascoLaura I Rossi
Jun 19, 2014·Chemistry : a European Journal·Lukáš KrivosudskýRóbert Gyepes

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