The conjugative plasmid pTR2030 encodes two bacteriophage defense mechanisms in lactococci, restriction modification (R+/M+) and abortive infection (Hsp+).

Applied and Environmental Microbiology
C HillT R Klaenhammer

Abstract

pTR2030 is a conjugative plasmid which encodes resistance to bacteriophage in lactococci by a mechanism that aborts the phage infection (Hsp+). Subcloning and in vivo deletion events showed that two independent mechanisms of resistance are located on a 13.6-kilobase Bg/II fragment cloned in pSA3; one mechanism is responsible for the abortive infection, and the other incodes a restriction modification system. The introduction of pTR2030 or the recombinant plasmid pTK6 resulted in the loss of a resident restriction modification plasmid in Lactococcus lactis NCK202 which was not previously identified.

References

Feb 1, 1988·Journal of Dairy Science·B R FrosethL L McKay
Mar 1, 1988·Biochimie·M E Sanders
Jan 1, 1985·Applied and Environmental Microbiology·M L Dao, J J Ferretti
Sep 1, 1983·Applied and Environmental Microbiology·D G Anderson, L L McKay
Dec 1, 1981·Applied and Environmental Microbiology·M E Sanders, T R Klaenhammer
Jun 1, 1986·Applied and Environmental Microbiology·W D Sing, T R Klaenhammer
Jun 1, 1975·Applied Microbiology·B E Terzaghi, W E Sandine

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Citations

Jul 11, 1998·Molecular Biotechnology·G M Djordjevic, T R Klaenhammer
Mar 4, 2000·Applied and Environmental Microbiology·E Durmaz, T R Klaenhammer
Jan 5, 2000·Applied and Environmental Microbiology·S A Walker, T R Klaenhammer
Jan 23, 2016·Dairy Science & Technology·Philip KelleherDouwe van Sinderen
Sep 1, 1990·FEMS Microbiology Reviews·L L McKay, K A Baldwin
May 23, 2002·FEMS Microbiology Letters·Mark Tangney, Gerald F Fitzgerald
Nov 6, 2002·Journal of Dairy Science·T R TulerT R Klaenhammer
Jan 1, 1993·Journal of Dairy Science·D A Romero, T R Klaenhammer
Apr 16, 1998·Molecular Microbiology·D J O'Sullivan, T R Klaenhammer
Dec 1, 1995·Molecular Biotechnology·P K Dinsmore, T R Klaenhammer
Nov 27, 2002·Applied and Environmental Microbiology·Mark Tangney, Gerald F Fitzgerald
Mar 26, 2019·Annual Review of Food Science and Technology·Todd Robert Klaenhammer
Apr 2, 1999·Applied and Environmental Microbiology·A FordeG F Fitzgerald
Mar 21, 1998·Applied and Environmental Microbiology·S A WalkerT R Klaenhammer
May 19, 1995·Gene·N NyengaardJ Josephsen
May 14, 2021·FEMS Microbiology Reviews·Alejandro González-DelgadoNicolás Toro
Nov 1, 1993·Applied and Environmental Microbiology·T P BeresfordA W Jarvis
Feb 1, 1992·Applied and Environmental Microbiology·D A Romero, T R Klaenhammer
Jan 1, 1991·Applied and Environmental Microbiology·C HillT R Klaenhammer
Feb 1, 1993·Applied and Environmental Microbiology·W D Sing, T R Klaenhammer
Aug 1, 1993·Applied and Environmental Microbiology·D J O'sullivanT R Klaenhammer
Aug 1, 1993·Applied and Environmental Microbiology·D J O'sullivan, T R Klaenhammer
Nov 1, 1990·Applied and Environmental Microbiology·C G de Los Reyes-GavilánJ P Accolas
Nov 14, 1997·Journal of Bacteriology·G M DjordjevicT R Klaenhammer
Nov 15, 1997·Applied and Environmental Microbiology·G M Djordjevic, T R Klaenhammer

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