The consensus statement on the locoregional treatment of abdominal sarcomatosis

Journal of Surgical Oncology
Carlo Riccardo RossiMarcello Deraco

Abstract

Abdominal sarcomatosis (AS) is a rare condition characterized by soft tissue sarcoma spreading throughout the abdomen, in the absence of extra-abdominal dissemination. Retroperitoneal sarcomas, pelvic sarcomas, particularly uterine leiomyosarcoma, and gastrointestinal stromal tumors (GISTs) most frequently give rise to AS. Systemic chemotherapy is the standard of care for AS from non-GIST sarcomas, but with an essentially palliative aim and major limitations. Innovative targeted therapies has deeply affected the natural history of GIST, at least in prolonging significantly survival in responsive patients. In this context, the notion that abdominal spread in the lack of extra-peritoneal lesions may typically occur in a number of patients, along with the dismal prognosis generally carried by AS, has prompted a few centers to perform cytoreductive surgery and perioperative intraperitoneal chemotherapy. To date, the rarity of these presentations makes it difficult to evaluate the clinical results and the role of combined local-regional treatment is still a matter of debate. This article presents the results of a group of experts from around the World trying to achieve a consensus statement in AS comprehensive management. A question...Continue Reading

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Citations

Dec 16, 2010·Clinical & Translational Oncology : Official Publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico·Wenceslao Vásquez JiménezSantiago González Moreno
Feb 4, 2012·Annals of Surgical Oncology·T Clark GamblinDavid L Bartlett
Aug 24, 2010·AJR. American Journal of Roentgenology·Tamara N OeiPablo R Ros
Feb 26, 2014·Annals of Oncology : Official Journal of the European Society for Medical Oncology·M ToulmondeUNKNOWN French Sarcoma Group
Feb 6, 2014·Annals of Oncology : Official Journal of the European Society for Medical Oncology·M ToulmondeUNKNOWN French Sarcoma Group
Aug 22, 2009·Journal of Surgical Oncology·Santiago González-MorenoLuis González-Bayón
Feb 7, 2013·Journal of Surgical Oncology·Joel M BaumgartnerHaroon A Choudry
Feb 6, 2009·Expert Review of Anticancer Therapy·Elisabetta PennacchioliAlessandro Gronchi
Oct 27, 2015·World Journal of Surgical Oncology·Maurizio CardiAngelo Di Giorgio
Jul 8, 2019·International Journal of Surgery Case Reports·Mingzhe CaiGrace Hwei Ching Tan
Jun 24, 2009·Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine·Kaiyumars B Contractor, Eric O Aboagye
Mar 1, 2014·Annals of Oncology : Official Journal of the European Society for Medical Oncology·M ToulmondeUNKNOWN French Sarcoma Group
Mar 1, 2014·Annals of Oncology : Official Journal of the European Society for Medical Oncology·M ToulmondeUNKNOWN French Sarcoma Group

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