The consolidation of object and context recognition memory involve different regions of the temporal lobe.

Learning & Memory
Israela BalderasFederico Bermudez-Rattoni

Abstract

These experiments investigated the involvement of several temporal lobe regions in consolidation of recognition memory. Anisomycin, a protein synthesis inhibitor, was infused into the hippocampus, perirhinal cortex, insular cortex, or basolateral amygdala of rats immediately after the sample phase of object or object-in-context recognition memory training. Anisomycin infused into perirhinal or insular cortices blocked long-term (24 h), but not short-term (90 min) object recognition memory. Infusions into the hippocampus or amygdala did not impair object recognition memory. Anisomycin infused into the hippocampus blocked long-term, but not short-term object-in-context recognition memory, whereas infusions administered into the perirhinal cortex, insular cortex, or amygdala did not affect object-in-context recognition memory. These results clearly indicate that distinct regions of the temporal lobe are differentially involved in long-term object and object-in-context recognition memory. Whereas perirhinal and insular cortices are required for consolidation of familiar objects, the hippocampus is necessary for consolidation of contextual information of recognition memory. Altogether, these results suggest that temporal lobe struct...Continue Reading

References

Nov 1, 1988·Behavioural Brain Research·A Ennaceur, J Delacour
Jan 1, 1993·Behavioral and Neural Biology·K RosenblumY Dudai
Nov 1, 1996·Neuron·R Muller
Jun 10, 1998·Progress in Neurobiology·M W Brown, J Z Xiang
Jan 21, 2000·Learning & Memory·E A BuffaloS M Zola
Mar 20, 2001·Nature Reviews. Neuroscience·M W Brown, J P Aggleton
Apr 13, 2001·Current Opinion in Neurobiology·E A Murray, B J Richmond
Apr 17, 2001·The Behavioral and Brain Sciences·J P Aggleton, M W Brown
Nov 21, 2001·Experimental Brain Research·D M BannermanM A Good
May 17, 2002·Current Opinion in Neurobiology·James L McGaugh, Benno Roozendaal
Aug 17, 2002·Trends in Neurosciences·James L McGaugh
Oct 16, 2002·Nature Neuroscience·Andrew P YonelinasRobert T Knight
Mar 4, 2003·Nature Reviews. Neuroscience·Charan Ranganath, Gregor Rainer
Feb 1, 1957·Journal of Neurology, Neurosurgery, and Psychiatry·W B SCOVILLE, B MILNER
Jan 30, 2004·Learning & Memory·Ranier GutiérrezFederico Bermudez-Rattoni
Feb 21, 2004·Nature Reviews. Neuroscience·Federico Bermúdez-Rattoni
Mar 24, 2004·Human Brain Mapping·Catherine L ReedEric Halgren
Jun 26, 2004·Annual Review of Neuroscience·James L McGaugh
Jul 2, 2004·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Boyer D WintersTimothy J Bussey
Sep 29, 2004·Proceedings of the National Academy of Sciences of the United States of America·Nicola J BroadbentRobert E Clark
Jan 7, 2005·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Boyer D Winters, Timothy J Bussey
Apr 29, 2005·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Boyer D Winters, Timothy J Bussey
Sep 17, 2005·Learning & Memory·Federico Bermudez-RattoniJames L McGaugh
Feb 1, 2006·Proceedings of the National Academy of Sciences of the United States of America·Emily L Malin, James L McGaugh
Apr 14, 2006·Proceedings of the National Academy of Sciences of the United States of America·Benno RoozendaalJames L McGaugh
Mar 16, 2007·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Gareth R I BarkerE Clea Warburton
Apr 10, 2007·Annual Review of Neuroscience·H EichenbaumC Ranganath

❮ Previous
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Citations

Apr 22, 2011·Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology·Ruth M BarrettMarcelo A Wood
Feb 6, 2010·Proceedings of the National Academy of Sciences of the United States of America·Julia Rosauro ClarkeJosé María Delgado-García
Jul 20, 2011·Proceedings of the National Academy of Sciences of the United States of America·Diego MoncadaHaydee Viola
Aug 6, 2011·Disease Models & Mechanisms·Ishita Das, Roger H Reeves
Jul 28, 2010·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Yong Sang Jo, Inah Lee
Jan 14, 2011·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Susan C McQuownMarcelo A Wood
Apr 8, 2010·The Journal of Neuroscience : the Official Journal of the Society for Neuroscience·Benno RoozendaalMarcelo A Wood
May 28, 2009·Proceedings of the National Academy of Sciences of the United States of America·Daniel P StefankoMarcelo A Wood
Dec 18, 2013·Psychopharmacology·Nabeel RkiehFrancesco Leri
Mar 31, 2010·Proceedings of the National Academy of Sciences of the United States of America·Valentina FerrettiAndrea Mele
Apr 29, 2014·Psychopharmacology·David ReissAbdel-Mouttalib Ouagazzal
Feb 10, 2016·Frontiers in Behavioral Neuroscience·Sofia KanatsouMarian Joëls
Oct 5, 2014·Neuroscience and Biobehavioral Reviews·M W Brown, P J Banks
Apr 15, 2014·Neuroscience·A P ArdaisL O Porciúncula
Oct 24, 2012·Behavioural Brain Research·Xavier De JaegerGrace S Pereira
Aug 20, 2011·Trends in Neurosciences·John LismanEmrah Duzel
Jul 19, 2011·International Journal of Developmental Neuroscience : the Official Journal of the International Society for Developmental Neuroscience·Rodrigo de Souza BalkFelix Alexandre Antunes Soares
Dec 23, 2009·Experimental Neurology·Yafit Kuttner HirshlerAnat Biegon
Apr 22, 2015·Behavioural Brain Research·Adam I RamsaranMark E Stanton
Sep 1, 2015·Brain Research·Natalia AriasJorge L Arias
Jan 11, 2014·Neurobiology of Learning and Memory·Federico Bermudez-Rattoni
Nov 1, 2008·The European Journal of Neuroscience·Vanesa De la CruzFederico Bermudez-Rattoni
Aug 21, 2010·The European Journal of Neuroscience·Paola Garcia-DelatorreFederico Bermúdez-Rattoni
May 20, 2015·The European Journal of Neuroscience·Panos ZanosTodd D Gould
May 15, 2013·Neurobiology of Learning and Memory·Charlotte K Callaghan, Aine M Kelly

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