The consumption of a Jerte Valley cherry product in humans enhances mood, and increases 5-hydroxyindoleacetic acid but reduces cortisol levels in urine

Experimental Gerontology
M GarridoA B Rodríguez

Abstract

Jerte Valley cherries contain high levels of tryptophan, serotonin, and melatonin. These molecules have been shown to be involved in mood regulation. It has been suggested that a complex inter-relationship between brain serotonin, circulating levels of cortisol (the major stress hormone), and the hypothalamus-pituitary-adrenal axis exists in the regulation of stress responses, where cortisol and serotonin act as markers of mood disturbances. Moreover there is growing evidence that altered HPA activity is associated with various age-related pathologies. The present study evaluated the effect of the ingestion of a Jerte Valley cherry-based product, compared to a placebo product, on urine cortisol and 5-hydroxyindoleacetic acid (5-HIAA) levels, and on mood in young, middle-aged, and elderly participants. Cortisol and 5-HIAA acid levels were measured by commercial enzyme-linked immunosorbent assay kits. The mood state profile was analysed using a visual analogue scale and the state-trait anxiety inventory. Our findings showed that the ingestion of the Jerte Valley cherry product decreased urinary cortisol and increased urinary 5-HIAA levels in all the experimental groups. Moreover, the cherry product was able to lessen anxiety stat...Continue Reading

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Citations

Aug 3, 2013·Journal of Medicinal Food·Maciej GąstołJustyna Dobrowolska-Iwanek
Jul 19, 2013·Oxidative Medicine and Cellular Longevity·M GarridoA B Rodríguez
Mar 14, 2013·Journal of Pineal Research·Yu ZhaoJin Kong
Dec 17, 2014·Journal of the Science of Food and Agriculture·Marcello Iriti, Elena Maria Varoni
Dec 7, 2018·Genes & Nutrition·Marynka UlaszewskaClaudine Manach
Mar 30, 2019·Genes & Nutrition·Mar Garcia-AloyCristina Andres-Lacueva
Mar 23, 2018·Nutrients·Darshan S KelleyKevin D Laugero

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