PMID: 2503350Jan 1, 1989Paper

The content of tumor angiogenesis factor in the blood serum of C57Bl/6 mice during the growth and metastasis of transplanted tumors

Eksperimentalʹnai︠a︡ onkologii︠a︡
I A Lisniak, E B Sopotsinskaia

Abstract

The tumour growth and metastasis development after the primary tumour removal is accompanied by the appearance of the tumour angiogenesis factor (TAF) in blood. The TAF level directly correlates with the volume of tumour cell masses. These results confirm the present notions about the close correlation of the tumour growth and neovascularization and may be used to control the activity of neovascularization and malignant growth.

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