The contribution of a collagen-fibrin patch (Tachosil) to prevent the postoperative lymphatic complications after groin lymphadenectomy: a double institution observational study

European Journal of Obstetrics, Gynecology, and Reproductive Biology
Alessandro BudaRodolfo Milani

Abstract

Postoperative morbidity associated with groin lymphadenectomy remain high and still represents a major concern for this patients. The aim of this study was to confirm the efficacy of TachoSil(®) in preventing postoperative complications after inguinofemoral lymphadenectomy for gynecological malignancy. An observational study was conducted to evaluate the incidence of postoperative complications among 49 patients (TachoSil(®) group=24; control group=25) underwent groin dissection enrolled in two Italian Department of Gynecology Oncology from 2011 to 2014. A total of 74 inguinal dissections were performed. Bilateral groin dissection was performed in 25 patients (Tachosil group=10; group 2=15). Patients in TachoSil(®) group showed a lower daily drainage volume with a mean volume of 84 ml (range 30-465) vs. 143 ml (range -72 to 413) in the control group (p=.004), and a lower total drainage volume with a mean of 540 ml (range 90-930) vs. 900 ml (range 200-3270) for Tachosil and control group, respectively. A lower incidence of lymphocyst required drainage, cellulitis, wound infection and late lymphedema was observed in TachoSil group even without reaching statistical significance. This observational study confirmed that the use of T...Continue Reading

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Citations

Apr 18, 2018·The British Journal of Surgery·M SchindlUNKNOWN Austrian Breast and Colorectal Cancer Study Group
Aug 14, 2018·Transplant International : Official Journal of the European Society for Organ Transplantation·Christopher K BurghuberGabriela A Berlakovich
Jun 24, 2017·International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society·Maria Luisa GasparriAndrea Papadia
Jun 28, 2018·Annals of Surgical Oncology·Walter Paul WeberUNKNOWN Swiss Group for Clinical Cancer Research (SAKK)
Jul 1, 2017·International Journal of Gynecological Cancer : Official Journal of the International Gynecological Cancer Society·Maria Luisa GasparriAndrea Papadia
Apr 20, 2020·Archives of Gynecology and Obstetrics·Peter DallMareike Bommert
Jul 28, 2020·American Journal of Obstetrics and Gynecology·Alon D AltmanGregg Nelson
Aug 14, 2020·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·Anastasios TranoulisStephen Attard Montalto

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