The contribution of aqueous humor cytology in the differential diagnosis of anterior uvea inflammations

Ocular Immunology and Inflammation
Christos D KalogeropoulosKonstantinos Psilas

Abstract

Cytology of the aqueous humor can confirm the diagnosis of many intraocular conditions by revealing inflammatory cells, ghost red cells, lens material, and microorganisms. The purpose of this study was to emphasize the contribution of aqueous humor fine needle aspiration cytology in cases where there is a clinical diagnostic dilemma whether an infectious or a noninfectious inflammatory process of the uvea is present. Collection of 0.15-0.2 ml aqueous humor was carried out with an insulin needle. The aspirated aqueous was then prepared for examination using either the Cytospin or the Thin-Prep technique and smears were stained with modified Papanikolaou and May-Grünwald-Giemsa stains. Cytology of the aqueous humor essentially facilitated the differential diagnosis in 16 cases with an anterior uveal inflammation clinical picture. The cases included phacoanaphylactic endophthalmitis (n = 6), chronic postoperative bacterial endophthalmitis (n = 3), phacolytic glaucoma (n = 2), ghost cell glaucoma (n = 2), metastatic endophthalmitis (n = 1), post-traumatic lenticular abscess (n = 1), and iridocyclitis (n = 1). Treatment of the cases was successful. In selected cases, cytology of the aqueous humor reveals specific, with regard to the...Continue Reading

References

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Citations

Sep 3, 2014·Ocular Immunology and Inflammation·Martin Sebastian ZinkernagelAndreas Ebneter
Mar 23, 2011·Journal of Glaucoma·Nikolaos MavrakanasTarek Shaarawy
Jul 31, 2007·Japanese Journal of Ophthalmology·Ko-hei MuraseMasahiko Usui
Jan 8, 2020·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·Eleanor Ngwe Nche, Radgonde Amer

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